Family Search for PF10239 (DUF2465)

PF10239 hits 13 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

FA98A_HUMAN / Q8NCA5 Protein FAM98A from Homo sapiens (Human) (see paper)
Aligns to 28:327 / 518 (57.9%), covers 99.7% of PF10239, 432.5 bits

• function: Positively stimulates PRMT1-induced protein arginine methylation (PubMed:28040436). Involved in skeletal homeostasis (By similarity). Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (By similarity).
  subunit: Interacts (via N- and C-terminus) with DDX1 (PubMed:28040436). Interacts (via N- and C-terminus) with C14orf166 (PubMed:28040436). Interacts with FAM98B (PubMed:28040436). Interacts with PLEKHM1 (via N- and C-terminus) (By similarity).

FA98A_MOUSE / Q3TJZ6 Protein FAM98A from Mus musculus (Mouse) (see paper)
Aligns to 28:327 / 515 (58.3%), covers 99.7% of PF10239, 431.9 bits

• function: Positively stimulates PRMT1-induced protein arginine methylation (By similarity). Involved in skeletal homeostasis (PubMed:27777970). Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (PubMed:27777970).
  subunit: Interacts (via N- and C-terminus) with DDX1 (By similarity). Interacts (via N- and C-terminus) with C14orf166 (By similarity). Interacts with FAM98B (By similarity). Interacts with PLEKHM1 (via N- and C-terminus) (PubMed:27777970).

FAM98B / Q52LJ0 tRNA-splicing ligase complex FAM98B component (EC 6.5.1.8) from Homo sapiens (see 2 papers)
FA98B_HUMAN / Q52LJ0 Protein FAM98B from Homo sapiens (Human) (see 5 papers)
Aligns to 34:330 / 433 (68.6%), covers 99.7% of PF10239, 428.6 bits

• function: Positively stimulates PRMT1-induced protein arginine dimethylated arginine methylation (PubMed:28040436).
  subunit: Homodimer (PubMed:28040436). Component of the tRNA-splicing ligase complex (PubMed:21311021, PubMed:24870230). Interacts with FAM98A (PubMed:28040436).

Or search for genetic data about PF10239 in the Fitness Browser