Family Search for PF10674 (Ycf54)

PF10674 hits 20 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

slr1780 / P72777 magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase auxiliary factor (EC 1.14.13.81) from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 3 papers)
Aligns to 29:120 / 133 (69.2%), covers 98.9% of PF10674, 140.8 bits

YCF54_ARATH / Q9LVM3 Protein YCF54, chloroplastic; Protein LOW CHLOROPHYLL ACCUMULATION from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Aligns to 74:164 / 211 (43.1%), covers 98.9% of PF10674, 111.8 bits

• function: Involved in the biosynthesis of chlorophyll; acts probably as a scaffolding factor in the MgProto monomethylester (MgProtoME) cyclase complex to stabilize CRD1/CHL27, the catalytic subunit which catalyzes the formation of a fifth isocyclic ring to tetrapyrroles to form protochlorophyllide (PubMed:29443418).
  subunit: Interacts with LFNR1 and CRD1/CHL27 in chloroplasts.
  disruption phenotype: Accumulation of MgProto monomethylester (MgProtoME) as a result of decreased CRD1/CHL27 accumulation leading to reduced cyclase activity of the MgProto monomethylester (MgProtoME) cyclase complex (PubMed:29443418). Leaf chlorosis due to a massive loss of photosynthetic protein complexes (PubMed:29443418).

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