Family Search for PF12263 (DUF3611)

PF12263 hits 6 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

TIC21_ARATH / Q9SHU7 Protein TIC 21, chloroplastic; Protein CHLOROPLAST IMPORT APPARATUS 5; AtCIA5; Protein PERMEASE IN CHLOROPLASTS 1; AtPIC1; Translocon at the inner envelope membrane of chloroplasts 21; AtTIC21 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Aligns to 107:283 / 296 (59.8%), covers 98.9% of PF12263, 179.4 bits

• function: Involved in chloroplast protein import across the inner envelope membrane. Acts also as a chloroplast permease regulating the iron transport and homeostasis. Involved in the uptake and sequestration of iron in plastids.
  subunit: Homomultimer. Part of the translocon complex.
  disruption phenotype: Seedling lethal when grown on soil. Albino or chlorotic dwarfed plants that accumulate unprocessed precursor proteins and chloroplast ferritin clusters when grown in vitro.

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