Family Search for PF14916 (CCDC92)

PF14916 hits 6 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

CCD92_HUMAN / Q53HC0 Coiled-coil domain-containing protein 92; Limkain beta-2 from Homo sapiens (Human) (see 3 papers)
Aligns to 24:80 / 331 (17.2%), covers 96.5% of PF14916, 84.3 bits

• function: Interferon-stimulated protein that plays a role in innate immunity. Strongly inhibits ebolavirus transcription and replication. Forms a complex with viral RNA-bound nucleocapsid NP and thereby prevents the transport of NP to the cell surface.
  subunit: Interacts with CEP164.
  subunit: (Microbial infection) Interacts with ebolavirus protein NP; this interaction sequesters NP in the cytoplasm.

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