Family Search for PF15763 (DUF4692)

PF15763 hits 1 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

RHEX_HUMAN / Q6ZWK4 Regulator of hemoglobinization and erythroid cell expansion protein; Regulator of human erythroid cell expansion protein from Homo sapiens (Human) (see paper)
Aligns to 7:172 / 172 (96.5%), covers 100.0% of PF15763, 277.9 bits

• function: Acts as a signaling transduction factor of the EPO-EPOR signaling pathway promoting erythroid cell differentiation (PubMed:25092874).
  subunit: Interacts with EPOR; this interaction occurs in a erythropoietin (EPO)-dependent manner (PubMed:25092874). Interacts with JAK2; this interaction occurs in a erythropoietin (EPO)-dependent manner (PubMed:25092874). Interacts (via tyrosine-phosphorylated form) with GRB2 (PubMed:25092874).

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