Family Search for PF16887 (DUF5081)

PF16887 hits 4 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

ESSE_STAA3 / A0A0H2XFI6 Type VII secretion system protein EsaE from Staphylococcus aureus (strain USA300) (see paper)
ESSE_STAA8 / Q2G181 Type VII secretion system protein EsaE from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
Aligns to 4:223 / 224 (98.2%), covers 99.6% of PF16887, 280.0 bits

• function: Component of the type VII secretion system (Ess). Plays a role in Esx protein secretion. Plays an essential role in the processing and secretion of EssD.
  subunit: Interacts with EssD.
  disruption phenotype: Deletion affects Esx protein secretion and the production of cytokines during bloodstream infection and also impacts the ability of staphylococci to establish infectious lesions and to manipulate cellular immune responses of the host.
• function: Component of the type VII secretion system (Ess). Plays a role in Esx protein secretion. Plays an essential role in the processing and secretion of EssD.
  subunit: Interacts with EssD (PubMed:27723728). Interacts with EssG (PubMed:27723728). Interacts with EssC (PubMed:27723728).

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