Family Search for PF04884 (UVB_sens_prot)
April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.
PF04884 hits 14 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.
RUSF1_DICDI / Q86K80 RUS family member 1 from Dictyostelium discoideum (Social amoeba) (see paper)
Aligns to 49:292 / 527 (46.3%), covers 98.8% of PF04884, 343.8 bits
- disruption phenotype: No visible phenotype.
RUS1_ARATH / Q7X6P3 Protein root UVB sensitive 1, chloroplastic; Protein WEAK AUXIN RESPONSE 3 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Aligns to 184:422 / 608 (39.3%), covers 97.5% of PF04884, 267.7 bits
- function: Involved in a root UV-B sensing pathway and in the protection against the hypersensitivity to very low-fluence-rate (VLF) UV-B. RSU1 and RUS2 are probably both negative modulators of the same UV-B perception pathway, which when overstimulated in the roots causes a block to postgermination development. Required for polar auxin transport by maintaining the proper levels of auxin transporters AUX1 (AC Q96247) and PIN proteins on the plasma membrane.
subunit: Interacts (via the DUF647 domain) with RUS2 (via the DUF647 domain).
disruption phenotype: No visible phenotype under normal growth conditions. Extremely stunted growth, failure to develop true postembryonic leaves and arrested primary root elongation, when grown in vitro.
RUS2_ARATH / Q9SJX7 Protein root UVB sensitive 2, chloroplastic; Protein WEAK AUXIN RESPONSE 1 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Aligns to 58:294 / 433 (54.7%), covers 97.9% of PF04884, 248.3 bits
- function: Involved in a root UV-B sensing pathway and in the protection against the hypersensitivity to very low-fluence-rate (VLF) UV-B. RSU1 and RUS2 are probably both negative modulators of the same UV-B perception pathway, which when overstimulated in the roots causes a block to postgermination development. Required for polar auxin transport and to maintain the normal levels of PIN proteins in the root.
subunit: Interacts (via the DUF647 domain) with RUS1 (via the DUF647 domain).
disruption phenotype: No visible phenotype under normal growth conditions. Extremely stunted growth, failure to develop true postembryonic leaves and arrested primary root elongation, when grown in vitro.
RUS6_ARATH / Q93YU2 Protein root UVB sensitive 6 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Aligns to 99:333 / 497 (47.3%), covers 97.1% of PF04884, 247.3 bits
- function: Required for normal embryo development.
Or search for genetic data about PF04884 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory