Family Search for PF06658 (DUF1168)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF06658 hits 6 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

PKRI1_MOUSE / Q9CWV6 PRKR-interacting protein 1; Protein C114 from Mus musculus (Mouse) (see paper)
Aligns to 42:180 / 186 (74.7%), covers 98.5% of PF06658, 157.4 bits

• function: Required for pre-mRNA splicing as component of the spliceosome (By similarity). Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity.
  subunit: Component of the pre-catalytic and post-catalytic spliceosome complexes (By similarity). Interacts with EIF2AK2.

PKRI1_HUMAN / Q9H875 PRKR-interacting protein 1 from Homo sapiens (Human) (see 2 papers)
Aligns to 42:178 / 184 (74.5%), covers 97.8% of PF06658, 155.8 bits

• function: Required for pre-mRNA splicing as component of the spliceosome (PubMed:28502770, PubMed:30705154). Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity (By similarity).
  subunit: Component of the pre-catalytic and post-catalytic spliceosome complexes (PubMed:28502770, PubMed:30705154). Interacts with EIF2AK2 (By similarity).

Or search for genetic data about PF06658 in the Fitness Browser