Family Search for PF07956 (DUF1690)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF07956 hits 5 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

MIC19_EMENI / Q5ASP0 MICOS complex subunit mic19 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
Aligns to 18:196 / 209 (85.6%), covers 100.0% of PF07956, 130.0 bits

• function: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane (By similarity). Involved in osmoadaptation.
  subunit: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.

MIC19_YEAST / P43594 MICOS complex subunit MIC19; Altered inheritance of mitochondria protein 13, mitochondrial; Mitochondrial contact site complex 19 kDa subunit from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 6 papers)
Aligns to 18:168 / 170 (88.8%), covers 100.0% of PF07956, 126.6 bits

• function: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
  subunit: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex, composed of at least MIC10, MIC12, MIC19, MIC26, MIC27 and MIC60. This complex was also known under the names MINOS or MitOS complex.
  disruption phenotype: Increases frequency of mitochondrial genome loss. Partially altered shape of the mitochondrial network with condensed, fragmented mitochondria accumulating at the periphery of cells. 20-40% of mitochondria exhibit an increased inner membrane surface and stacks of lamellar cristae disconnected from the inner boundary membrane.

Or search for genetic data about PF07956 in the Fitness Browser