Family Search for PF10166 (DUF2368)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF10166 hits 5 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

PLRKT_RAT / D4ACN8 Plasminogen receptor (KT); Plg-R(KT) from Rattus norvegicus (Rat) (see paper)
Aligns to 1:134 / 147 (91.2%), covers 100.0% of PF10166, 197.0 bits

• function: Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator- dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metalloproteinase activation, such as of MMP2 and MMP9 (By similarity).
  subunit: Interacts with PLAT (By similarity). Interacts with PLAUR.

PLRKT_HUMAN / Q9HBL7 Plasminogen receptor (KT); Plg-R(KT) from Homo sapiens (Human) (see 2 papers)
Aligns to 1:134 / 147 (91.2%), covers 100.0% of PF10166, 192.9 bits

• function: Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator- dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metalloproteinase activation, such as of MMP2 and MMP9.
  subunit: Interacts with PLAT and PLAUR.

PLRKT_MOUSE / Q9D3P8 Plasminogen receptor (KT); Plg-R(KT) from Mus musculus (Mouse) (see 3 papers)
Aligns to 1:134 / 147 (91.2%), covers 100.0% of PF10166, 192.8 bits

• function: Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator- dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metalloproteinase activation, such as of MMP2 and MMP9.
  subunit: Interacts with PLAT. Interacts with PLAUR (By similarity).

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