Family Search for PF10674 (Ycf54)

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PF10674 hits 20 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

slr1780 / P72777 magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase auxiliary factor (EC 1.14.13.81) from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 3 papers)
Aligns to 29:120 / 133 (69.2%), covers 98.9% of PF10674, 140.8 bits

YCF54_ARATH / Q9LVM3 Protein YCF54, chloroplastic; Protein LOW CHLOROPHYLL ACCUMULATION from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Aligns to 74:164 / 211 (43.1%), covers 98.9% of PF10674, 111.8 bits

• function: Involved in the biosynthesis of chlorophyll; acts probably as a scaffolding factor in the MgProto monomethylester (MgProtoME) cyclase complex to stabilize CRD1/CHL27, the catalytic subunit which catalyzes the formation of a fifth isocyclic ring to tetrapyrroles to form protochlorophyllide (PubMed:29443418).
  subunit: Interacts with LFNR1 and CRD1/CHL27 in chloroplasts.
  disruption phenotype: Accumulation of MgProto monomethylester (MgProtoME) as a result of decreased CRD1/CHL27 accumulation leading to reduced cyclase activity of the MgProto monomethylester (MgProtoME) cyclase complex (PubMed:29443418). Leaf chlorosis due to a massive loss of photosynthetic protein complexes (PubMed:29443418).

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