Family Search for PF11326 (DUF3128)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF11326 hits 6 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

EMI1_YEAST / Q04406 Early meiotic induction protein 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
Aligns to 104:181 / 187 (41.7%), covers 100.0% of PF11326, 90.9 bits

• function: Involved in sporulation. Required for the full activation of the early meiotic inducer IME1.

CV039_MOUSE / Q3U595 Synaptic plasticity regulator PANTS; Plasticity-associated neural transcript short from Mus musculus (Mouse) (see 2 papers)
Aligns to 10:88 / 105 (75.2%), covers 98.8% of PF11326, 59.2 bits

• function: Negatively regulates long-term potentiation and modulates adult synaptic plasticity (PubMed:35771867). Stabilizes the interaction of RTN4 isoform A/Nogo-A with its receptors, inhibiting clustering of postsynaptic AMPA receptors at synaptic sites (PubMed:35771867). Upon neuronal stimulation, degraded at synapses, reducing RTN4 signaling and allowing AMPA receptor clustering at individual synapses (PubMed:35771867).
  subunit: Interacts with RTN4 isoform A/Nogo-A; the interaction results in enhanced RTN4-mediated inhibition of AMPA receptor clustering (PubMed:35771867). Also interacts with NCAM1, RANBP2 and CCT8 (PubMed:35771867).

Or search for genetic data about PF11326 in the Fitness Browser