Family Search for PF11753 (DUF3310)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF11753 hits 13 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

1.7 / P03781 nucleotide kinase gp1.7 from Escherichia phage T7 (see paper)
NUCK_BPT7 / P03781 Nucleotide kinase gp1.7; Gene product 1.7; Gp1.7 from Escherichia phage T7 (Bacteriophage T7) (see 3 papers)
Aligns to 122:185 / 196 (32.7%), covers 98.3% of PF11753, 77.0 bits

• function: Nucleotide kinase that catalyzes the phosphorylation of dGMP and dTMP to dGDP and dTDP (PubMed:18599435, PubMed:20497505). A double mutation in this protein and the RecBCD inhibitor gp5.9 protein allow phage to overcome the retron Ec48 bacteriophage defense system. This protein alone when overexpressed in E.coli does not cause growth arrest; Y128C may be a silent mutation (PubMed:33157039).
  subunit: Dodecamer.

SAV_BPLP2 / B6UL32 SaV protein; Gene product 26; Gp26 from Lactococcus phage p2 (Lactococcus lactis bacteriophage p2) (see paper)
Aligns to 4:65 / 128 (48.4%), covers 91.5% of PF11753, 36.9 bits

• function: Involved in the sensitivity of the virus to the host AbiV system.

Or search for genetic data about PF11753 in the Fitness Browser