Family Search for PF13926 (DUF4211)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF13926 hits 9 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

YE06_SCHPO / O13803 Uncharacterized protein C17H9.06c from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
Aligns to 366:499 / 601 (22.3%), covers 99.3% of PF13926, 116.8 bits

QSER1_HUMAN / Q2KHR3 Glutamine and serine-rich protein 1 from Homo sapiens (Human) (see paper)
Aligns to 1485:1646 / 1735 (9.3%), covers 96.4% of PF13926, 81.8 bits

• function: Plays an essential role in the protection and maintenance of transcriptional and developmental programs. Protects many bivalent promoters and poised enhancers from hypermethylation, showing a marked preference for these regulatory elements over other types of promoters or enhancers. Mechanistically, cooperates with TET1 and binds to DNA in a common complex to inhibit the binding of DNMT3A/3B and therefore de novo methylation.
  subunit: Interacts with TET1.

PRR12_MOUSE / E9PYL2 Proline-rich protein 12 from Mus musculus (Mouse) (see paper)
Aligns to 1817:1944 / 2035 (6.3%), covers 83.9% of PF13926, 46.3 bits

PRR12_HUMAN / Q9ULL5 Proline-rich protein 12 from Homo sapiens (Human) (see 3 papers)
Aligns to 1819:1945 / 2036 (6.2%), covers 83.2% of PF13926, 46.1 bits

Or search for genetic data about PF13926 in the Fitness Browser