Family Search for PF14739 (DUF4472)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF14739 hits 4 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

CCD78_XENLA / Q66KE8 Coiled-coil domain-containing protein 78; xCCDC78 from Xenopus laevis (African clawed frog) (see paper)
Aligns to 60:166 / 559 (19.1%), covers 100.0% of PF14739, 121.6 bits

• function: Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells (G1/0) and not in S phase. Essential for centriole amplification and is required for cep152 localization to the deuterosome.

CCD78_HUMAN / A2IDD5 Coiled-coil domain-containing protein 78; hsCCDC78 from Homo sapiens (Human) (see 2 papers)
Aligns to 54:165 / 438 (25.6%), covers 98.1% of PF14739, 100.9 bits

• function: Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells (G1/0) and not in S phase. Essential for centriole amplification and is required for CEP152 localization to the deuterosome.

Or search for genetic data about PF14739 in the Fitness Browser