Family Search for PF15923 (DUF4745)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF15923 hits 2 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

GRRE1_HUMAN / O15063 Granule associated Rac and RHOG effector protein 1; GARRE1 from Homo sapiens (Human) (see 2 papers)
Aligns to 59:187 / 1070 (12.1%), covers 99.2% of PF15923, 182.4 bits

• function: Acts as an effector of RAC1 (PubMed:31871319). Associates with CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation (PubMed:29395067). May also play a role in miRNA silencing machinery (PubMed:29395067).
  subunit: Interacts with AGO2 and TNRC6A.

Or search for genetic data about PF15923 in the Fitness Browser