Comparing 14979 FitnessBrowser__Keio:14979 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 16 hits to proteins with known functional sites (download)
P31133 Putrescine-binding periplasmic protein PotF from Escherichia coli (strain K12) (see 3 papers)
100% identity, 100% coverage: 1:370/370 of query aligns to 1:370/370 of P31133
6ye7A E.Coli's putrescine receptor potf complexed with cadaverine (see paper)
100% identity, 92% coverage: 29:369/370 of query aligns to 1:341/341 of 6ye7A
6ye6A E.Coli's putrescine receptor potf complexed with agmatine (see paper)
100% identity, 92% coverage: 29:369/370 of query aligns to 1:341/341 of 6ye6A
6ye0B E.Coli's putrescine receptor potf complexed with putrescine (see paper)
100% identity, 92% coverage: 29:369/370 of query aligns to 1:341/341 of 6ye0B
1a99A Putrescine receptor (potf) from e. Coli (see paper)
100% identity, 92% coverage: 29:369/370 of query aligns to 1:341/341 of 1a99A
7oyxB E.Coli's putrescine receptor variant potf/d (4jdf) with mutations e39d y87s f88y s247d in complex with spermidine (see paper)
99% identity, 92% coverage: 29:370/370 of query aligns to 1:342/347 of 7oyxB
7oywA E.Coli's putrescine receptor variant potf/d (4jdf) with mutations e39d f88l s247d in complex with spermidine (see paper)
98% identity, 92% coverage: 29:370/370 of query aligns to 1:342/348 of 7oywA
7oyvA E.Coli's putrescine receptor variant potf/d (4jdf) with mutations e39d f88a s247d in complex with spermidine (see paper)
98% identity, 92% coverage: 29:369/370 of query aligns to 1:341/341 of 7oyvA
Q9I6J1 Putrescine-binding periplasmic protein SpuD from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
56% identity, 100% coverage: 1:370/370 of query aligns to 2:367/367 of Q9I6J1
3ttmA Crystal structure of spud in complex with putrescine (see paper)
59% identity, 92% coverage: 28:369/370 of query aligns to 1:341/341 of 3ttmA
Q9I6J0 Spermidine-binding periplasmic protein SpuE from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
55% identity, 97% coverage: 12:370/370 of query aligns to 9:365/365 of Q9I6J0
3ttnA Crystal structures of polyamine receptors spud and spue from pseudomonas aeruginosa (see paper)
56% identity, 91% coverage: 31:367/370 of query aligns to 1:335/335 of 3ttnA
P0AFK9 Spermidine/putrescine-binding periplasmic protein; SPBP from Escherichia coli (strain K12) (see 3 papers)
36% identity, 85% coverage: 26:341/370 of query aligns to 23:320/348 of P0AFK9
Sites not aligning to the query:
1poy1 Spermidine/putrescine-binding protein complexed with spermidine (dimer form) (see paper)
36% identity, 84% coverage: 31:341/370 of query aligns to 3:295/323 of 1poy1
Sites not aligning to the query:
7xjnA Structure of vcpotd1 in complex with norspermidine
35% identity, 84% coverage: 30:341/370 of query aligns to 3:295/322 of 7xjnA
Sites not aligning to the query:
4eqbA 1.5 angstrom crystal structure of spermidine/putrescine abc transporter substrate-binding protein potd from streptococcus pneumoniae strain canada mdr_19a in complex with calcium and hepes
31% identity, 85% coverage: 30:345/370 of query aligns to 2:297/323 of 4eqbA
Sites not aligning to the query:
>14979 FitnessBrowser__Keio:14979
MTALNKKWLSGLVAGALMAVSVGTLAAEQKTLHIYNWSDYIAPDTVANFEKETGIKVVYD
VFDSNEVLEGKLMAGSTGFDLVVPSASFLERQLTAGVFQPLDKSKLPEWKNLDPELLKLV
AKHDPDNKFAMPYMWATTGIGYNVDKVKAVLGENAPVDSWDLILKPENLEKLKSCGVSFL
DAPEEVFATVLNYLGKDPNSTKADDYTGPATDLLLKLRPNIRYFHSSQYINDLANGDICV
AIGWAGDVWQASNRAKEAKNGVNVSFSIPKEGAMAFFDVFAMPADAKNKDEAYQFLNYLL
RPDVVAHISDHVFYANANKAATPLVSAEVRENPGIYPPADVRAKLFTLKVQDPKIDRVRT
RAWTKVKSGK
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory