Comparing 18321 b4297 KpLE2 phage-like element; predicted dehydratase (NCBI) to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 12 hits to proteins with known functional sites (download)
6ovtA Crystal structure of ilvd from mycobacterium tuberculosis (see paper)
34% identity, 78% coverage: 89:602/655 of query aligns to 52:546/562 of 6ovtA
Sites not aligning to the query:
P9WKJ5 Dihydroxy-acid dehydratase; DAD; EC 4.2.1.9 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
34% identity, 78% coverage: 89:602/655 of query aligns to 65:559/575 of P9WKJ5
Sites not aligning to the query:
Q9LIR4 Dihydroxy-acid dehydratase, chloroplastic; AthDHAD; DAD; EC 4.2.1.9 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
32% identity, 71% coverage: 120:581/655 of query aligns to 132:567/608 of Q9LIR4
Sites not aligning to the query:
8hs0A The mutant structure of dhad v178w
32% identity, 71% coverage: 120:581/655 of query aligns to 94:529/570 of 8hs0A
Sites not aligning to the query:
Q1JUQ1 L-arabonate dehydratase; L-arabinonate dehydratase; EC 4.2.1.25 from Azospirillum brasilense (see paper)
33% identity, 68% coverage: 136:580/655 of query aligns to 99:521/583 of Q1JUQ1
Sites not aligning to the query:
B5ZZ34 L-arabinonate dehydratase; ArDHT; D-fuconate dehydratase; Galactonate dehydratase; L-arabonate dehydratase; EC 4.2.1.25; EC 4.2.1.67; EC 4.2.1.6 from Rhizobium leguminosarum bv. trifolii (strain WSM2304) (see 2 papers)
31% identity, 81% coverage: 77:607/655 of query aligns to 42:539/579 of B5ZZ34
5j85A Ser480ala mutant of l-arabinonate dehydratase (see paper)
30% identity, 81% coverage: 77:607/655 of query aligns to 39:536/576 of 5j85A
8ej0A Crystal structure of fe-s cluster-dependent dehydratase from paralcaligenes ureilyticus in complex with mg
31% identity, 82% coverage: 58:597/655 of query aligns to 10:523/568 of 8ej0A
8epzA Crystal structure of fe-s cluster-dependent dehydratase from paralcaligenes ureilyticus in complex with mn
31% identity, 82% coverage: 58:597/655 of query aligns to 11:524/569 of 8epzA
5oynA Crystal structure of d-xylonate dehydratase in holo-form (see paper)
31% identity, 66% coverage: 155:588/655 of query aligns to 119:542/589 of 5oynA
Sites not aligning to the query:
Q9A9Z2 D-xylonate dehydratase; XyDHT; Gluconate dehydratase; EC 4.2.1.82; EC 4.2.1.39 from Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) (see 2 papers)
31% identity, 66% coverage: 155:588/655 of query aligns to 125:548/595 of Q9A9Z2
Sites not aligning to the query:
7m3kA Crystal structure of galactonate dehydratase from brucella melitensis biovar abortus 2308
29% identity, 77% coverage: 136:640/655 of query aligns to 96:572/587 of 7m3kA
Sites not aligning to the query:
>18321 b4297 KpLE2 phage-like element; predicted dehydratase (NCBI)
MSVRNIFADESHDIYTVRTHADGPDGELPLTAEMLINRPSGDLFGMTMNAGMGWSPDELD
RDGILLLSTLGGLRGADGKPVALALHQGHYELDIQMKAAAEVIKANHALPYAVYVSDPCD
GRTQGTTGMFDSLPYRNDASMVMRRLIRSLPDAKAVIGVASCDKGLPATMMALAAQHNIA
TVLVPGGATLPAKDGEDNGKVQTIGARFANGELSLQDARRAGCKACASSGGGCQFLGTAG
TSQVVAEGLGLAIPHSALAPSGEPVWREIARASARAALNLSQKGITTREILTDKAIENAM
TVHAAFGGSTNLLLHIPAIAHQAGCHIPTVDDWIRINKRVPRLVSVLPNGPVYHPTVNAF
MAGGVPEVMLHLRSLGLLHEDVMTVTGSTLKENLDWWEHSERRQRFKQLLLDQEQINADE
VIMSPQQAKARGLTSTITFPVGNIAPEGSVIKSTAIDPSMIDEQGIYYHKGVAKVYLSEK
SAIYDIKHDKIKAGDILVIIGVGPSGTGMEETYQVTSALKHLSYGKHVSLITDARFSGVS
TGACIGHVGPEALAGGPIGKLRTGDLIEIKIDCRELHGEVNFLGTRSDEQLPSQEEATAI
LNARPSHQDLLPDPELPDDTRLWAMLQAVSGGTWTGCIYDVNKIGAALRDFMNKN
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory