Comparing 349859 FitnessBrowser__Btheta:349859 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 9 hits to proteins with known functional sites (download)
6n2oC 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus with 2-oxoglutarate, coenzyme a and succinyl-coa bound (see paper)
29% identity, 99% coverage: 2:293/295 of query aligns to 259:571/572 of 6n2oC
Sites not aligning to the query:
6n2oA 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus with 2-oxoglutarate, coenzyme a and succinyl-coa bound (see paper)
29% identity, 99% coverage: 2:293/295 of query aligns to 259:571/572 of 6n2oA
Sites not aligning to the query:
6n2nA Crystal structure of 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus (see paper)
29% identity, 99% coverage: 2:293/295 of query aligns to 259:571/572 of 6n2nA
Sites not aligning to the query:
Q96XT2 2-oxoacid:ferredoxin oxidoreductase 2, subunit alpha; OFOR2; EC 1.2.7.11 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
35% identity, 35% coverage: 1:104/295 of query aligns to 300:403/628 of Q96XT2
Sites not aligning to the query:
5b47A 2-oxoacid:ferredoxin oxidoreductase 2 from sulfolobus tokodai - pyruvate complex (see paper)
35% identity, 35% coverage: 1:104/295 of query aligns to 299:402/627 of 5b47A
Sites not aligning to the query:
5b46A 2-oxoacid:ferredoxin oxidoreductase 2 from sulfolobus tokodai - ligand free form (see paper)
35% identity, 35% coverage: 1:104/295 of query aligns to 299:402/627 of 5b46A
Sites not aligning to the query:
5b48A 2-oxoacid:ferredoxin oxidoreductase 1 from sulfolobus tokodai (see paper)
30% identity, 43% coverage: 1:127/295 of query aligns to 268:394/576 of 5b48A
Sites not aligning to the query:
Q96Y66 2-oxoacid:ferredoxin oxidoreductase 1, subunit alpha; OFOR1; EC 1.2.7.11 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
32% identity, 38% coverage: 1:113/295 of query aligns to 300:412/627 of Q96Y66
Sites not aligning to the query:
P72578 2-oxoacid:ferredoxin oxidoreductase subunit alpha; OFOR; EC 1.2.7.11 from Sulfolobus sp. (see 2 papers)
32% identity, 38% coverage: 1:113/295 of query aligns to 300:412/632 of P72578
Sites not aligning to the query:
>349859 FitnessBrowser__Btheta:349859
MVYGGAGSGKMVLTSSSSPGVSLKQEGISYIAGAELPCLIVNVMRGGPGLGTIQPSQADY
FQTVKGGGHGDYRLIALAPASVQEMADFVALGFELAFKYRNPAIILADGVIGQMMEKVVL
PAQKPRRTDAEVIEQCPWAATGKAKGRKPNIITSLELKPEAMEINNIRFQAKYKQIEENE
VRFEEINCEDAEYLIVAFGSMARIGQKAMELAREKGIKVGILRPITLWPFPSKAIAAYAD
KVKGMLVTELNAGQMIEDVRLAVNGKVKVEHFGRLGGIVPDPDEIVTALEEKIIK
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory