Comparing 5208646 FitnessBrowser__PV4:5208646 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 14 hits to proteins with known functional sites (download)
3wlxA Crystal structure of low-specificity l-threonine aldolase from escherichia coli
57% identity, 97% coverage: 1:324/335 of query aligns to 1:320/331 of 3wlxA
4rjyA Crystal structure of e. Coli l-threonine aldolase in complex with a non-covalently uncleaved bound l-serine substrate (see paper)
57% identity, 95% coverage: 1:319/335 of query aligns to 1:315/332 of 4rjyA
4lnmA Structure of escherichia coli threonine aldolase in complex with serine (see paper)
57% identity, 95% coverage: 1:319/335 of query aligns to 1:315/331 of 4lnmA
4lnlA Structure of escherichia coli threonine aldolase in complex with allo- thr (see paper)
57% identity, 95% coverage: 1:319/335 of query aligns to 1:315/332 of 4lnlA
4lnjA Structure of escherichia coli threonine aldolase in unliganded form (see paper)
57% identity, 95% coverage: 1:319/335 of query aligns to 1:315/332 of 4lnjA
O07051 L-allo-threonine aldolase; L-allo-TA; L-allo-threonine acetaldehyde-lyase; EC 4.1.2.49 from Aeromonas jandaei (see paper)
55% identity, 100% coverage: 2:335/335 of query aligns to 4:336/338 of O07051
3wgcB Aeromonas jandaei l-allo-threonine aldolase h128y/s292r double mutant (see paper)
55% identity, 100% coverage: 2:335/335 of query aligns to 3:333/333 of 3wgcB
3wgbD Crystal structure of aeromonas jandaei l-allo-threonine aldolase (see paper)
54% identity, 100% coverage: 2:335/335 of query aligns to 2:324/324 of 3wgbD
1lw5B X-ray structure of l-threonine aldolase (low-specificity) in complex with glycine (see paper)
45% identity, 100% coverage: 1:335/335 of query aligns to 1:339/343 of 1lw5B
1lw4B X-ray structure of l-threonine aldolase (low-specificity) in complex with l-allo-threonine (see paper)
45% identity, 100% coverage: 1:335/335 of query aligns to 1:339/343 of 1lw4B
1jg8D Crystal structure of threonine aldolase (low-specificity)
45% identity, 100% coverage: 1:335/335 of query aligns to 2:340/344 of 1jg8D
Q8RXU4 Low-specificity L-threonine aldolase 1; Threonine aldolase 1; EC 4.1.2.48 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
42% identity, 96% coverage: 2:324/335 of query aligns to 6:338/358 of Q8RXU4
5vyeB Crystal structure of l-threonine aldolase from pseudomonas putida
28% identity, 54% coverage: 4:185/335 of query aligns to 6:191/344 of 5vyeB
Sites not aligning to the query:
O50584 Low specificity L-threonine aldolase; Low specificity L-TA; EC 4.1.2.48 from Pseudomonas sp. (strain NCIMB 10558) (see paper)
30% identity, 54% coverage: 4:185/335 of query aligns to 8:193/346 of O50584
Sites not aligning to the query:
>5208646 FitnessBrowser__PV4:5208646
MIDFRSDTVTQPTAAMRRAMADAQVGDDVYGDDPSVNRLEAMAAERFGFDSALFTSSGTQ
ANLLALMSHCDRGDEYLCGQQAHNYKFEGGGAAVLGSIQPQPLTNQPDGSILLSDIEAAI
KPDDFHFARTRLLSLENTIGGKVLPQSYLAEAQALAFNKRLKIHLDGARIANAAVAHNLD
IADITQYFDSVSICLSKGLCAPVGSLLLGDERLINKARRWRKMLGGGMRQAGILAVAGEI
ALNEQVSRLAVDHENARYLAEQLSCLDEFEVDLGEVQTNMLFARVVEGVAIDKLATSLKA
SGILISPGKTLRMVTHADIRLEDIDLFIDKLKSLL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory