Comparing AO353_23490 FitnessBrowser__pseudo3_N2E3:AO353_23490 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
8ewoA Crystal structure of putative glyoxylase ii from pseudomonas aeruginosa
72% identity, 100% coverage: 1:255/255 of query aligns to 2:259/259 of 8ewoA
6rz0A Crystal structure of escherichia coli glyoxalase ii
48% identity, 100% coverage: 2:255/255 of query aligns to 1:251/251 of 6rz0A
2qedA Crystal structure of salmonella thyphimurium lt2 glyoxalase ii (see paper)
47% identity, 100% coverage: 2:255/255 of query aligns to 2:252/252 of 2qedA
Q8ZRM2 Hydroxyacylglutathione hydrolase; Glyoxalase II; Glx II; EC 3.1.2.6 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
47% identity, 100% coverage: 2:255/255 of query aligns to 1:251/251 of Q8ZRM2
Q9SID3 Hydroxyacylglutathione hydrolase 2, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
42% identity, 100% coverage: 2:255/255 of query aligns to 71:324/324 of Q9SID3
2q42A Ensemble refinement of the protein crystal structure of glyoxalase ii from arabidopsis thaliana gene at2g31350 (see paper)
42% identity, 100% coverage: 2:255/255 of query aligns to 1:254/254 of 2q42A
O24496 Hydroxyacylglutathione hydrolase cytoplasmic; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
40% identity, 100% coverage: 2:255/255 of query aligns to 1:256/258 of O24496
1qh5B Human glyoxalase ii with s-(n-hydroxy-n-bromophenylcarbamoyl) glutathione (see paper)
38% identity, 100% coverage: 2:255/255 of query aligns to 1:255/260 of 1qh5B
1qh5A Human glyoxalase ii with s-(n-hydroxy-n-bromophenylcarbamoyl) glutathione (see paper)
38% identity, 100% coverage: 2:255/255 of query aligns to 1:255/260 of 1qh5A
1qh3A Human glyoxalase ii with cacodylate and acetate ions present in the active site (see paper)
38% identity, 100% coverage: 2:255/255 of query aligns to 1:255/260 of 1qh3A
Q16775 Hydroxyacylglutathione hydrolase, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Homo sapiens (Human) (see paper)
38% identity, 100% coverage: 2:255/255 of query aligns to 49:303/308 of Q16775
2p18A Crystal structure of the leishmania infantum glyoxalase ii (see paper)
31% identity, 92% coverage: 2:236/255 of query aligns to 13:274/283 of 2p18A
4ysbA Crystal structure of ethe1 from myxococcus xanthus (see paper)
29% identity, 74% coverage: 1:188/255 of query aligns to 1:191/225 of 4ysbA
Q9C8L4 Persulfide dioxygenase ETHE1 homolog, mitochondrial; Glyoxalase II; Glx II; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
29% identity, 78% coverage: 11:209/255 of query aligns to 62:274/294 of Q9C8L4
2gcuA X-ray structure of gene product from arabidopsis thaliana at1g53580 (see paper)
29% identity, 78% coverage: 11:209/255 of query aligns to 13:225/244 of 2gcuA
2xf4A Crystal structure of salmonella enterica serovar typhimurium ycbl (see paper)
34% identity, 53% coverage: 3:138/255 of query aligns to 4:160/210 of 2xf4A
Sites not aligning to the query:
O95571 Persulfide dioxygenase ETHE1, mitochondrial; Ethylmalonic encephalopathy protein 1; Hepatoma subtracted clone one protein; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Homo sapiens (Human) (see 4 papers)
26% identity, 82% coverage: 13:222/255 of query aligns to 35:248/254 of O95571
Sites not aligning to the query:
4chlB Human ethylmalonic encephalopathy protein 1 (hethe1) (see paper)
25% identity, 82% coverage: 13:222/255 of query aligns to 19:232/237 of 4chlB
7ev5A Crystal structure of bleg-1 b3 metallo-beta-lactamase (see paper)
31% identity, 65% coverage: 3:167/255 of query aligns to 4:191/209 of 7ev5A
5ve5A Crystal structure of persulfide dioxygenase rhodanese fusion protein with rhodanese domain inactivating mutation (c314s) from burkholderia phytofirmans in complex with glutathione (see paper)
30% identity, 62% coverage: 11:169/255 of query aligns to 14:178/350 of 5ve5A
Sites not aligning to the query:
>AO353_23490 FitnessBrowser__pseudo3_N2E3:AO353_23490
MIQISALPAFTDNYIWLLQDHRSQRCAVVDPGDAAPVQAWLAMHPGWQLSDILVTHHHHD
HVGGVEQLKKATGATVYGPASENIPGRDIALNDNDRVSVLGREFDVYAVPGHTLGHIAYY
HQGLLFCGDTLFAAGCGRLFEGTPAQMHHSLSRLAALPEDTLVYCTHEYTLSNLRFAAAV
EPNNPDIAERLEKVSQLRESGGMSLPSTLALEKLTNPFLRTGETSVKEKVDERNGQDNRA
PSEVFAALRAWKDTF
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory