Comparing Ac3H11_1188 FitnessBrowser__acidovorax_3H11:Ac3H11_1188 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 4 hits to proteins with known functional sites (download)
1b4uB Protocatechuate 4,5-dioxygenase (ligab) in complex with protocatechuate (pca) (see paper)
60% identity, 99% coverage: 2:294/296 of query aligns to 1:278/298 of 1b4uB
3wr9A Crystal structure of the anaerobic desb-gallate complex (see paper)
41% identity, 99% coverage: 2:295/296 of query aligns to 1:275/416 of 3wr9A
Sites not aligning to the query:
3wkuA Crystal structure of the anaerobic desb-gallate complex (see paper)
40% identity, 99% coverage: 2:295/296 of query aligns to 1:270/407 of 3wkuA
Sites not aligning to the query:
P0ABR9 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase; 3-carboxyethylcatechol 2,3-dioxygenase; EC 1.13.11.16 from Escherichia coli (strain K12) (see paper)
32% identity, 53% coverage: 41:198/296 of query aligns to 35:180/314 of P0ABR9
Sites not aligning to the query:
>Ac3H11_1188 FitnessBrowser__acidovorax_3H11:Ac3H11_1188
MAKITASVFTSHVPAIGAAMDLGKTHEDYWKPVFAGYEFGKQWVKDHKPDVIFLVYNDHA
TAFSLDLIPTFAIGTAAEYEVADEGFGPRPVPMVIGHPDLAAHIAQSVIQQDFDLTIVNK
MAVDHGLTVPLSLMFGEQDPVKGAWPCPVIPFAVNVVQYPVPSGRRCYNLGQAIRKAVES
YDEDINVHIWGTGGMSHQLQGPRAGLINKEFDNAFLDKLIADPEAAASIPHIDYVREAGS
EGIELVMWLIARGAMSDVARAATADVAGGNPPKLAHRFYHVPASNTAVGHLILENT
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory