Comparing Echvi_3019 FitnessBrowser__Cola:Echvi_3019 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 18 hits to proteins with known functional sites (download)
P75804 Aldose sugar dehydrogenase YliI; Asd; Soluble aldose sugar dehydrogenase YliI; EC 1.1.5.- from Escherichia coli (strain K12) (see paper)
40% identity, 85% coverage: 46:373/387 of query aligns to 22:355/371 of P75804
2g8sA Crystal structure of the soluble aldose sugar dehydrogenase (asd) from escherichia coli in the apo-form (see paper)
40% identity, 83% coverage: 51:373/387 of query aligns to 5:333/348 of 2g8sA
7cdyA Crystal structure of glucose dehydrogenase
36% identity, 84% coverage: 50:373/387 of query aligns to 2:331/346 of 7cdyA
7cgzA Glucose dehydrogenase
34% identity, 84% coverage: 50:373/387 of query aligns to 2:306/321 of 7cgzA
2ismB Crystal structure of the putative oxidoreductase (glucose dehydrogenase) (ttha0570) from thermus theromophilus hb8
33% identity, 83% coverage: 51:373/387 of query aligns to 4:311/333 of 2ismB
3a9hA Crystal structure of pqq-dependent sugar dehydrogenase holo-form (see paper)
32% identity, 84% coverage: 48:373/387 of query aligns to 3:312/338 of 3a9hA
Sites not aligning to the query:
3a9gA Crystal structure of pqq-dependent sugar dehydrogenase apo-form (see paper)
32% identity, 84% coverage: 48:373/387 of query aligns to 3:312/338 of 3a9gA
1cruA Soluble quinoprotein glucose dehydrogenase from acinetobacter calcoaceticus in complex with pqq and methylhydrazine (see paper)
30% identity, 60% coverage: 47:277/387 of query aligns to 15:267/448 of 1cruA
Sites not aligning to the query:
P13650 Quinoprotein glucose dehydrogenase B; Glucose dehydrogenase B [pyrroloquinoline-quinone]; Soluble glucose dehydrogenase; s-GDH; EC 1.1.5.2 from Acinetobacter calcoaceticus (see paper)
30% identity, 60% coverage: 47:277/387 of query aligns to 39:293/478 of P13650
Sites not aligning to the query:
1cq1A Soluble quinoprotein glucose dehydrogenase from acinetobacter calcoaceticus in complex with pqqh2 and glucose (see paper)
31% identity, 60% coverage: 47:277/387 of query aligns to 15:263/444 of 1cq1A
Sites not aligning to the query:
1c9uA Crystal structure of the soluble quinoprotein glucose dehydrogenase in complex with pqq (see paper)
31% identity, 60% coverage: 47:277/387 of query aligns to 15:263/444 of 1c9uA
Sites not aligning to the query:
5minB Apo form of the soluble pqq-dependent glucose dehydrogenase from acinetobacter calcoaceticus
30% identity, 60% coverage: 47:277/387 of query aligns to 15:269/453 of 5minB
Sites not aligning to the query:
3dasA Structure of the pqq-bound form of aldose sugar dehydrogenase (adh) from streptomyces coelicolor
28% identity, 83% coverage: 52:373/387 of query aligns to 12:310/334 of 3dasA
Sites not aligning to the query:
2wfxB Crystal structure of the complex between human hedgehog-interacting protein hip and sonic hedgehog in the presence of calcium (see paper)
26% identity, 49% coverage: 49:237/387 of query aligns to 3:207/417 of 2wfxB
Sites not aligning to the query:
7pgmB Hhip-c in complex with heparin (see paper)
25% identity, 49% coverage: 49:237/387 of query aligns to 4:207/427 of 7pgmB
Sites not aligning to the query:
7pgnB Hhp-c in complex with glycosaminoglycan mimic sos (see paper)
25% identity, 49% coverage: 49:237/387 of query aligns to 4:212/438 of 7pgnB
Sites not aligning to the query:
7pgnA Hhp-c in complex with glycosaminoglycan mimic sos (see paper)
25% identity, 49% coverage: 49:237/387 of query aligns to 5:213/437 of 7pgnA
Sites not aligning to the query:
Q96QV1 Hedgehog-interacting protein; HHIP; HIP from Homo sapiens (Human) (see 3 papers)
25% identity, 49% coverage: 49:237/387 of query aligns to 217:432/700 of Q96QV1
Sites not aligning to the query:
>Echvi_3019 FitnessBrowser__Cola:Echvi_3019
MKNPIASLSVTPPLVIFALILVGSVSCAQDKRPEVRENTPPIEDDPKNYTTETIVEDINN
PWGMALLPDGGILVTEKAGELIYAKDGEKKIIPGTPDVVSKGQGGLLDIILHPDYATNGW
IYFTYSSGEGEEDGAHTAVMRAKFHGNSLTDQEVLYKATPNTDKGQHFGSRMAFDEEGYL
YFSIGERGERDVNPQDITRDGGKIYRIHDDGSIPNDNPFFNEEDAKKAIFSYGHRNPQGM
IFHPVYNEIWVNEHGPQGGDEINIVEKGGNFGWPVVSYGINYDDSILTEETSKEGMEQPL
YYWVPSIAPCGFALVPEETYPQWAGNLLVGSLKFQYLEMLSLDGKQVTKRTKLMDGAGRL
RNVKIGPDNHIYVGIQGTGIVKIIPNR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory