Comparing GFF3717 FitnessBrowser__psRCH2:GFF3717 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
5x7uA Trehalose synthase from thermobaculum terrenum (see paper)
42% identity, 99% coverage: 3:536/539 of query aligns to 2:541/546 of 5x7uA
5gtwA The n253r mutant structures of trehalose synthase from deinococcus radiodurans display two different active-site conformations
37% identity, 98% coverage: 3:532/539 of query aligns to 1:545/548 of 5gtwA
3zo9A The structure of trehalose synthase (tres) of mycobacterium smegmatis (see paper)
37% identity, 99% coverage: 5:535/539 of query aligns to 7:547/549 of 3zo9A
3zoaA The structure of trehalose synthase (tres) of mycobacterium smegmatis in complex with acarbose (see paper)
37% identity, 99% coverage: 5:535/539 of query aligns to 6:546/548 of 3zoaA
4lxfA Crystal structure of m. Tuberculosis tres (see paper)
37% identity, 98% coverage: 3:532/539 of query aligns to 30:567/570 of 4lxfA
5jy7B Complex of mycobacterium smegmatis trehalose synthase with maltokinase (see paper)
37% identity, 99% coverage: 5:535/539 of query aligns to 19:568/571 of 5jy7B
3zoaB The structure of trehalose synthase (tres) of mycobacterium smegmatis in complex with acarbose (see paper)
37% identity, 99% coverage: 5:535/539 of query aligns to 19:568/571 of 3zoaB
A0R6E0 Trehalose synthase/amylase TreS; Maltose alpha-D-glucosyltransferase; MTase; EC 3.2.1.1; EC 5.4.99.16 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see 2 papers)
37% identity, 99% coverage: 5:535/539 of query aligns to 35:584/593 of A0R6E0
5ykbD The n253f mutant structure of trehalose synthase from deinococcus radiodurans reveals an open active-site conformation (see paper)
36% identity, 98% coverage: 3:532/539 of query aligns to 1:521/523 of 5ykbD
4lxfB Crystal structure of m. Tuberculosis tres (see paper)
35% identity, 98% coverage: 3:532/539 of query aligns to 30:543/546 of 4lxfB
2ze0A Alpha-glucosidase gsj (see paper)
32% identity, 98% coverage: 2:529/539 of query aligns to 1:525/531 of 2ze0A
4aieA Structure of glucan-1,6-alpha-glucosidase from lactobacillus acidophilus ncfm (see paper)
31% identity, 97% coverage: 5:526/539 of query aligns to 3:529/537 of 4aieA
5wczA Crystal structure of wild-type mall from bacillus subtilis with ts analogue 1-deoxynojirimycin (see paper)
29% identity, 97% coverage: 5:526/539 of query aligns to 2:548/556 of 5wczA
4mazA The structure of mall mutant enzyme v200s from bacillus subtilus (see paper)
29% identity, 97% coverage: 5:526/539 of query aligns to 2:551/559 of 4mazA
O06994 Oligo-1,6-glucosidase 1; Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase 1; Sucrase-isomaltase 1; Isomaltase 1; EC 3.2.1.10 from Bacillus subtilis (strain 168) (see paper)
29% identity, 97% coverage: 5:526/539 of query aligns to 4:553/561 of O06994
4m56A The structure of wild-type mall from bacillus subtilis (see paper)
29% identity, 97% coverage: 5:526/539 of query aligns to 2:547/555 of 4m56A
7lv6B The structure of mall mutant enzyme s536r from bacillus subtilis
29% identity, 97% coverage: 5:526/539 of query aligns to 2:551/559 of 7lv6B
8ibkA Crystal structure of bacillus sp. Ahu2216 gh13_31 alpha-glucosidase e256q/n258g in complex with maltotriose (see paper)
29% identity, 91% coverage: 5:494/539 of query aligns to 3:509/546 of 8ibkA
Sites not aligning to the query:
4wlcA Structure of dextran glucosidase with glucose (see paper)
30% identity, 93% coverage: 1:503/539 of query aligns to 1:511/536 of 4wlcA
2zidA Crystal structure of dextran glucosidase e236q complex with isomaltotriose (see paper)
30% identity, 93% coverage: 1:503/539 of query aligns to 1:511/536 of 2zidA
>GFF3717 FitnessBrowser__psRCH2:GFF3717
MRPLWYRNAAIYQIDPTLFRDSNGDGCGDLRGITERLDYIRGLGCTAVWLMPFYQSPFED
AGYDISDHLQVDERFGDLADIVALLEKAEELGLHVIIELVVQHTSIQHKWFQEARRDRNS
PYRDYYIWADEPDDFMEPIFPTVEDSIWTWDEEAGQYYRHLFYKHEPDLDLTNPRVIHEI
ERIMSFWLRLGVSGFRIDAAVHMVRQAGGGELEKGYWLLEHMRDFVTMRRPETVLLGEID
TDPDKYVEYFGDEADRVTLLLDFWTNNHLFLSLARQQAEPLVRALNSQPLPPSHSQYALW
IRNHDELSLDRLEEDERNEVMDTFAPDENMRAYNRGIRRRLAPMLDGDERRIAATHALLF
SLPGTPIIRYGEEIGMGDDLDRPERLAVRTPMQWSNEPNAGFSCTKGELAAPVIDEGPFT
YEKINVFAQTLRSDSLMARTGNMIRTRIGLREIGIGKRTTVEVNDPAVFAIRHDNGSTVL
MLVNLADQETTVEITDDDLQDMVDVLADCDYDQPEGTPLKIRLGPYGYRWLRRKQQLFG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory