Comparing HSERO_RS02180 FitnessBrowser__HerbieS:HSERO_RS02180 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4wjmA Crystal structure of fructokinase from brucella abortus 2308 with bound amppnp
30% identity, 92% coverage: 11:286/301 of query aligns to 12:304/312 of 4wjmA
3gbuA Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with atp
26% identity, 93% coverage: 10:289/301 of query aligns to 5:286/302 of 3gbuA
3ih0A Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with amp-pnp
26% identity, 93% coverage: 10:288/301 of query aligns to 6:286/304 of 3ih0A
Q8ZKR2 Aminoimidazole riboside kinase; AIRs kinase; EC 2.7.1.223 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
29% identity, 84% coverage: 9:260/301 of query aligns to 9:264/319 of Q8ZKR2
Sites not aligning to the query:
1tz3A Crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside (see paper)
29% identity, 84% coverage: 9:260/301 of query aligns to 5:253/299 of 1tz3A
1tz6A Crystal structure of aminoimidazole riboside kinase from salmonella enterica complexed with aminoimidazole riboside and atp analog (see paper)
29% identity, 84% coverage: 9:260/301 of query aligns to 5:253/297 of 1tz6A
Sites not aligning to the query:
1v1bA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound atp (see paper)
31% identity, 88% coverage: 30:293/301 of query aligns to 33:295/300 of 1v1bA
Q53W83 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
31% identity, 88% coverage: 30:293/301 of query aligns to 33:295/309 of Q53W83
1v1aA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound 2- keto-3-deoxygluconate and adp (see paper)
31% identity, 88% coverage: 30:293/301 of query aligns to 33:295/301 of 1v1aA
Sites not aligning to the query:
3lkiB Crystal structure of fructokinase with bound atp from xylella fastidiosa
30% identity, 97% coverage: 8:298/301 of query aligns to 6:317/322 of 3lkiB
3iq0B Crystal structure of a putative ribokinase ii in complex with atp and mg+2 from e.Coli
26% identity, 93% coverage: 12:290/301 of query aligns to 13:295/308 of 3iq0B
5eynA Crystal structure of fructokinase from vibrio cholerae o395 in fructose, adp, beryllium trifluoride and calcium ion bound form
27% identity, 81% coverage: 11:255/301 of query aligns to 8:256/306 of 5eynA
Sites not aligning to the query:
5yggA Crystal structure of fructokinase double-mutant (t261c-h108c) from vibrio cholerae o395 in fructose, adp and potassium ion bound form (see paper)
27% identity, 81% coverage: 11:255/301 of query aligns to 12:260/310 of 5yggA
Sites not aligning to the query:
7fcaD Pfkb(mycobacterium marinum) (see paper)
28% identity, 93% coverage: 8:286/301 of query aligns to 5:282/282 of 7fcaD
7aghA Crystal structure of sf kinase yihv from e. Coli in complex with amppnp-mg (see paper)
25% identity, 89% coverage: 24:292/301 of query aligns to 32:284/295 of 7aghA
8cqxA Ribokinase from t.Sp mutant a92g
27% identity, 92% coverage: 23:298/301 of query aligns to 29:298/300 of 8cqxA
7ag6A Crystal structure of sf kinase yihv from e. Coli in complex with sulfofructose (sf), adp-mg (see paper)
24% identity, 89% coverage: 24:292/301 of query aligns to 32:286/302 of 7ag6A
Sites not aligning to the query:
7agkA Crystal structure of e. Coli sf kinase (yihv) in complex with product sulfofructose phosphate (sfp) (see paper)
24% identity, 89% coverage: 24:292/301 of query aligns to 32:286/298 of 7agkA
Sites not aligning to the query:
P32143 Sulfofructose kinase; SF kinase; EC 2.7.1.184 from Escherichia coli (strain K12) (see paper)
24% identity, 89% coverage: 24:292/301 of query aligns to 32:286/298 of P32143
Sites not aligning to the query:
6a8cA Ribokinase from leishmania donovani with adp (see paper)
26% identity, 75% coverage: 30:255/301 of query aligns to 50:283/327 of 6a8cA
Sites not aligning to the query:
>HSERO_RS02180 FitnessBrowser__HerbieS:HSERO_RS02180
MTQSAAFVVFGEALTDFIRQPDEQWRAIPGGACWNVARAAARLGVPTGYAGSVSTDVFGA
ELYALTQAAGLDMRFTQQYAKAPLLAMVTSTTPPDYFFIGDDSADLHFDPQRLPAGWLDD
AQVLHFGCISLTREPLASRLLQIAQEAARRNKKIAFDPNWRKLMDSPSYRLLFQQLLSLS
HYVKVSDEDLERLFPGDTNALATLQSLAPQAEILYTLGAKGMQWIKGEQVIDQPAYRVEV
IDTVGCGDASMGGWIASQLRQPDAPAQVHLQCAAAGAAIAASKAGAYAATWDEVQALIAH
A
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory