SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

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Fitness BLAST: loading...

Comparing NIAGMN_24555 to proteins with known functional sites using BLASTp with E ≤ 0.001.

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Found 1 hits to proteins with known functional sites (download)

P27360 Antiholin from Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21) (see 2 papers)
76% identity, 100% coverage: 1:71/71 of query aligns to 1:71/71 of P27360

query
sites
P27360

M
|
M

Y
x
K

Q
x
S

M
|
M

E

D

K

K

I

I

T

S

T

T

G

G

V

I

S

A

Y

Y

T

G

T

T

S

S

A

A

V

G

G

S

T

A

G

G

Y

Y

W

W

L

F

L

L

Q

Q

L

W

L

L

D

D

K

Q

V

V

S

S

P

P

S

S

Q

Q

W

W

V

A

A

A

I

I

G

G

V

V

L

L

G

G

S

S

L

L

L

V

F

L

G

G

L

F

L

L

T

T

Y

Y

L

L

T

T

N

N

L

L

Y

Y

F

F

K

K

I

I

R

R

E

E

D

D

R

R

R

R

K

K

A

A

A

A

R

R

G

G

E

E

M1 (= M1) mutation to L: No effect on lysis activity.
MKS 1:3 (≠ MYQ 1:3) modified: Variant sequence, Missing (in isoform Holin)
K2 (≠ Y2) mutation K->R,S,T: Decrease in lysis inhibition by isoform Antiholin.
M4 (= M4) mutation to L: Complete loss of lysis activity.

Query Sequence

>NIAGMN_24555
MYQMEKITTGVSYTTSAVGTGYWLLQLLDKVSPSQWVAIGVLGSLLFGLLTYLTNLYFKI
REDRRKAARGE

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory