Comparing Pf1N1B4_1025 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_1025 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 8 hits to proteins with known functional sites (download)
Q88E47 Homogentisate 1,2-dioxygenase; HGDO; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase; EC 1.13.11.5 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
82% identity, 100% coverage: 1:434/434 of query aligns to 1:433/433 of Q88E47
4aq6D Substrate bound homogentisate 1,2-dioxygenase (see paper)
83% identity, 98% coverage: 8:434/434 of query aligns to 1:427/427 of 4aq6D
3zdsA Structure of homogentisate 1,2-dioxygenase in complex with reaction intermediates of homogentisate with oxygen. (see paper)
83% identity, 98% coverage: 10:434/434 of query aligns to 1:425/425 of 3zdsA
3zdsF Structure of homogentisate 1,2-dioxygenase in complex with reaction intermediates of homogentisate with oxygen. (see paper)
83% identity, 98% coverage: 10:434/434 of query aligns to 2:426/426 of 3zdsF
3zdsC Structure of homogentisate 1,2-dioxygenase in complex with reaction intermediates of homogentisate with oxygen. (see paper)
83% identity, 98% coverage: 10:434/434 of query aligns to 2:426/426 of 3zdsC
Q93099 Homogentisate 1,2-dioxygenase; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase; EC 1.13.11.5 from Homo sapiens (Human) (see 13 papers)
50% identity, 98% coverage: 10:434/434 of query aligns to 4:439/445 of Q93099
1ey2A Human homogentisate dioxygenase with fe(ii) (see paper)
50% identity, 94% coverage: 10:418/434 of query aligns to 3:413/419 of 1ey2A
Q9Y041 Homogentisate 1,2-dioxygenase; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase; EC 1.13.11.5 from Caenorhabditis elegans (see paper)
49% identity, 97% coverage: 10:429/434 of query aligns to 7:433/437 of Q9Y041
>Pf1N1B4_1025 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_1025
MNLDSTAPALAYQSGFGNEFSSEALPGALPVGQNSPQKAPYGLYTELFSGTAFTMTRSEA
RRTWMYRIQPSANHPAFVKLDRQLAGGPLGEVTPNRLRWNPLDMPTEPTDFIDGLVSMAA
NSGAEKPSGISIYNYRANRSMERVFFNADGELLLVPQLGRLRIATELGVLELEPLEIAVL
PRGLKFRVELLDPQARGYIAENHGAPLRLPDLGPIGSNGLANPRDFLTPVAHYENLKQPT
TLVQKFLGQLWGCELDHSPLNVVAWHGNNVPYKYDLRRFNTIGTVSFDHPDPSIFTVLTS
PTSVHGLANLDFVIFPPRWMVAEKTFRPPWFHRNLMNEFMGLIQGEYDAKAEGFVPGGAS
LHSCMSAHGPDGETCTKAINAELAPAKIDNTMAFMFETSQVLRPSRFALDCPQLQNNYDA
CWATLPATFDPTRR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory