Comparing SM_b20099 FitnessBrowser__Smeli:SM_b20099 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
5gtwA The n253r mutant structures of trehalose synthase from deinococcus radiodurans display two different active-site conformations
43% identity, 98% coverage: 6:538/544 of query aligns to 3:544/548 of 5gtwA
5ykbD The n253f mutant structure of trehalose synthase from deinococcus radiodurans reveals an open active-site conformation (see paper)
42% identity, 98% coverage: 6:538/544 of query aligns to 3:520/523 of 5ykbD
5x7uA Trehalose synthase from thermobaculum terrenum (see paper)
40% identity, 98% coverage: 6:536/544 of query aligns to 4:525/546 of 5x7uA
Sites not aligning to the query:
3zo9A The structure of trehalose synthase (tres) of mycobacterium smegmatis (see paper)
39% identity, 98% coverage: 6:536/544 of query aligns to 7:532/549 of 3zo9A
3zoaA The structure of trehalose synthase (tres) of mycobacterium smegmatis in complex with acarbose (see paper)
39% identity, 98% coverage: 6:536/544 of query aligns to 6:531/548 of 3zoaA
Sites not aligning to the query:
4lxfA Crystal structure of m. Tuberculosis tres (see paper)
40% identity, 98% coverage: 6:539/544 of query aligns to 32:567/570 of 4lxfA
5jy7B Complex of mycobacterium smegmatis trehalose synthase with maltokinase (see paper)
39% identity, 98% coverage: 6:536/544 of query aligns to 19:553/571 of 5jy7B
3zoaB The structure of trehalose synthase (tres) of mycobacterium smegmatis in complex with acarbose (see paper)
39% identity, 98% coverage: 6:536/544 of query aligns to 19:553/571 of 3zoaB
A0R6E0 Trehalose synthase/amylase TreS; Maltose alpha-D-glucosyltransferase; MTase; EC 3.2.1.1; EC 5.4.99.16 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see 2 papers)
39% identity, 98% coverage: 6:536/544 of query aligns to 35:569/593 of A0R6E0
4lxfB Crystal structure of m. Tuberculosis tres (see paper)
39% identity, 98% coverage: 6:539/544 of query aligns to 32:543/546 of 4lxfB
2ze0A Alpha-glucosidase gsj (see paper)
33% identity, 90% coverage: 3:493/544 of query aligns to 1:484/531 of 2ze0A
4aieA Structure of glucan-1,6-alpha-glucosidase from lactobacillus acidophilus ncfm (see paper)
30% identity, 91% coverage: 4:497/544 of query aligns to 1:501/537 of 4aieA
5wczA Crystal structure of wild-type mall from bacillus subtilis with ts analogue 1-deoxynojirimycin (see paper)
29% identity, 90% coverage: 6:495/544 of query aligns to 2:512/556 of 5wczA
4m56A The structure of wild-type mall from bacillus subtilis (see paper)
29% identity, 90% coverage: 6:495/544 of query aligns to 2:512/555 of 4m56A
4wlcA Structure of dextran glucosidase with glucose (see paper)
29% identity, 92% coverage: 3:502/544 of query aligns to 2:504/536 of 4wlcA
2zidA Crystal structure of dextran glucosidase e236q complex with isomaltotriose (see paper)
29% identity, 92% coverage: 3:502/544 of query aligns to 2:504/536 of 2zidA
4mazA The structure of mall mutant enzyme v200s from bacillus subtilus (see paper)
29% identity, 90% coverage: 6:495/544 of query aligns to 2:515/559 of 4mazA
O06994 Oligo-1,6-glucosidase 1; Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase 1; Sucrase-isomaltase 1; Isomaltase 1; EC 3.2.1.10 from Bacillus subtilis (strain 168) (see paper)
28% identity, 90% coverage: 4:495/544 of query aligns to 2:517/561 of O06994
7lv6B The structure of mall mutant enzyme s536r from bacillus subtilis
29% identity, 90% coverage: 6:495/544 of query aligns to 2:515/559 of 7lv6B
5brpA Crystal structure of bacillus licheniformis trehalose-6-phosphate hydrolase (trea), mutant r201q, in complex with png (see paper)
27% identity, 99% coverage: 5:542/544 of query aligns to 2:555/555 of 5brpA
>SM_b20099 FitnessBrowser__Smeli:SM_b20099
MKEAPWFSSSVIYGIDVRRFSDGNGDGIGDFIGLKERVSYLHYLGIDCVWLSPFFRSPFA
DNGYDVSDYYSIDPVLGTLDDFLDFLHAAGEQGIRVVVDLVANHTSSEHPWFQAARRDAR
CRFRDYYVWSESPPPVAPDNKTAFPGEESSVWTYDDLAQAYYFHKFRHFQPDLNIANPAV
RDELLRVVDYWLTLGVDGFRVDAAPFVIGETGIEHADPRDPQGFLREMRKLVDGRRQDGL
LLGEADLAPEKLRSYFGDGKLDLLFNFVLCAAFAASLAGQKADPIGQALSIMPEPPPHRG
WANFLRNLDELNLDRLPEDIREETFAAFAPDEEMRIYGRGIRRRLAPMLDGNRARIELAF
SLLLSSPGVPLILYGDEIGLGEDLSRPGREPVRVPMQWNAGSNAGFSTAQRAKLVQPPVT
DGPFSFKRVNVEAQREDPGSLLNRVRAMILARRRHELFNRGRPVMLHTGDPALFALAYSD
GTELFVVLHNLSDGKRRAELELPGAIDARLNDILGEGEVELSGQRLAIGLGPFGYVWLHS
GKKD
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory