Comparing SM_b20453 FitnessBrowser__Smeli:SM_b20453 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 15 hits to proteins with known functional sites (download)
3dr2A Structural and functional analyses of xc5397 from xanthomonas campestris: a gluconolactonase important in glucose secondary metabolic pathways (see paper)
42% identity, 91% coverage: 19:293/303 of query aligns to 29:296/299 of 3dr2A
3e5zA X-ray structure of the putative gluconolactonase in protein family pf08450. Northeast structural genomics consortium target drr130.
39% identity, 96% coverage: 13:302/303 of query aligns to 8:290/290 of 3e5zA
Q9A9Z1 D-xylonolactone lactonase; Xylono-1,5-lactonase; EC 3.1.1.110 from Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) (see paper)
28% identity, 90% coverage: 31:303/303 of query aligns to 7:266/289 of Q9A9Z1
7pldB Caulobacter crescentus xylonolactonase with (r)-4-hydroxy-2- pyrrolidone (see paper)
28% identity, 90% coverage: 31:303/303 of query aligns to 7:266/289 of 7pldB
7plbB Caulobacter crescentus xylonolactonase with d-xylose (see paper)
28% identity, 90% coverage: 31:303/303 of query aligns to 7:266/289 of 7plbB
8dk0A Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound (s)gamma- valerolactone (see paper)
25% identity, 84% coverage: 33:287/303 of query aligns to 12:271/293 of 8dk0A
8djzA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound product (see paper)
25% identity, 84% coverage: 33:287/303 of query aligns to 12:271/293 of 8djzA
8djfA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound tetrahedral intermediate (see paper)
25% identity, 84% coverage: 33:287/303 of query aligns to 12:271/293 of 8djfA
7risA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound phosphate (see paper)
24% identity, 84% coverage: 33:287/303 of query aligns to 10:271/293 of 7risA
7rizA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound 2-hydroxyquinoline (see paper)
24% identity, 84% coverage: 33:287/303 of query aligns to 10:284/306 of 7rizA
5gx1A Luciferin-regenerating enzyme collected with serial synchrotron rotational crystallography with accumulated dose of 1.1 mgy (1st measurement) (see paper)
29% identity, 36% coverage: 179:286/303 of query aligns to 159:270/307 of 5gx1A
Sites not aligning to the query:
5d9bA Luciferin-regenerating enzyme solved by siras using xfel (refined against native data) (see paper)
29% identity, 36% coverage: 179:286/303 of query aligns to 159:270/307 of 5d9bA
Sites not aligning to the query:
Q15493 Regucalcin; RC; Gluconolactonase; GNL; Senescence marker protein 30; SMP-30; EC 3.1.1.17 from Homo sapiens (Human) (see 2 papers)
24% identity, 86% coverage: 27:288/303 of query aligns to 10:264/299 of Q15493
4gncA Human smp30/gnl-1,5-ag complex (see paper)
24% identity, 86% coverage: 27:288/303 of query aligns to 9:263/298 of 4gncA
Sites not aligning to the query:
3g4hA Crystal structure of human senescence marker protein-30 (zinc bound) (see paper)
24% identity, 86% coverage: 27:288/303 of query aligns to 8:262/297 of 3g4hA
>SM_b20453 FitnessBrowser__Smeli:SM_b20453
MADSPHYDIRDERFRSLIVGSAALEELYRGCRWAEGPVWFSDLDCLIWSDIPNQRMMRWT
PDGGASVFRSPSNYVNGNTRDREGRLISCEHGGRRVTRTEHDGRITVLADIYEGKRLNSP
NDAVVHSDGSIWFTDPTYGILSDYEGHKAEPEQPTRNVYRIDPLSGAIKAVVRDFIQPNG
LAFSPDEARLYIADSGSAKHEVPSHIRVFDVAADGVLANDRYFCSIDNGNPDGFRFDVAG
NLWCSAADGVHCFDTGGTLLGKILVPQTVSNLTFGGPKKNRLFITATQSLYSIYTATNGV
QYP
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory