Comparing SM_b20587 FitnessBrowser__Smeli:SM_b20587 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 5 hits to proteins with known functional sites (download)
Q0S7P9 Cholesterol ring-cleaving hydrolase IpdA subunit; (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA hydrolase alpha subunit; COCHEA-CoA hydrolase alpha subunit; EC 4.1.99.- from Rhodococcus jostii (strain RHA1) (see paper)
26% identity, 66% coverage: 97:286/286 of query aligns to 98:296/296 of Q0S7P9
6co9A Crystal structure of rhodococcus jostii rha1 ipdab cochea-coa complex (see paper)
26% identity, 66% coverage: 97:286/286 of query aligns to 97:295/295 of 6co9A
Sites not aligning to the query:
8i40A Crystal structure of asct from trypanosoma brucei in complex with coa.
25% identity, 78% coverage: 1:222/286 of query aligns to 2:231/467 of 8i40A
Sites not aligning to the query:
8i3yD Crystal structure of asct from trypanosoma brucei in complex with succinyl-coa.
25% identity, 78% coverage: 1:222/286 of query aligns to 2:231/471 of 8i3yD
8i3yA Crystal structure of asct from trypanosoma brucei in complex with succinyl-coa.
25% identity, 78% coverage: 1:222/286 of query aligns to 2:231/459 of 8i3yA
Sites not aligning to the query:
>SM_b20587 FitnessBrowser__Smeli:SM_b20587
MARIMSLAEAVEENVRDGDTVAMEGFTHLIPYAAGHEVIRQGRKDLFLVRMTPDILYDQL
IGVGAARGMKFSWGGNPGVGSLHRFRDAVENQWPRPLEIEEHSHAAMANAYEAGAGNLPF
AAFRGYIGADLPKVNLNIRSVTCPFTGEVLAAVPAIRPDVTIIHAQRADRNGNVLIEGIV
GVQKEAVLAARRSIVTVEEIVDELSPPSPNSVVLPGWAVTAVAHVPGGAFPSYAHGYYPR
SNAFYIRWDEIARDRETFTAWIRENVLAAKPEDFARHAAKTAAKVA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory