Comparing Synpcc7942_1653 FitnessBrowser__SynE:Synpcc7942_1653 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8gobA Crystal structure of glycerol dehydrogenase in the presence of NAD+ (see paper)
44% identity, 90% coverage: 24:381/398 of query aligns to 3:359/367 of 8gobA
8goaA Crystal structure of glycerol dehydrogenase in the absence of NAD+ (see paper)
44% identity, 90% coverage: 24:381/398 of query aligns to 3:359/367 of 8goaA
5zxlA Structure of glda from e.Coli (see paper)
44% identity, 90% coverage: 24:381/398 of query aligns to 3:359/367 of 5zxlA
P0A9S5 Glycerol dehydrogenase; GDH; GLDH; (R)-aminopropanol dehydrogenase; 1,2-propanediol dehydrogenase; D-1-amino-2-propanol oxidoreductase; EC 1.1.1.6; EC 1.1.1.75 from Escherichia coli (strain K12) (see paper)
44% identity, 90% coverage: 24:381/398 of query aligns to 3:359/367 of P0A9S5
4mcaA Crystal structure of glycerol dehydrogenase from serratia to 1.9a
41% identity, 91% coverage: 24:387/398 of query aligns to 3:365/367 of 4mcaA
1kq3A Crystal structure of a glycerol dehydrogenase (tm0423) from thermotoga maritima at 1.5 a resolution (see paper)
41% identity, 89% coverage: 27:381/398 of query aligns to 7:358/364 of 1kq3A
Q9WYQ4 Glycerol dehydrogenase; GDH; GLDH; EC 1.1.1.6 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
41% identity, 89% coverage: 27:381/398 of query aligns to 6:357/364 of Q9WYQ4
P32816 Glycerol dehydrogenase; GDH; GLDH; GlyDH; EC 1.1.1.6 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see 2 papers)
39% identity, 92% coverage: 22:387/398 of query aligns to 3:367/370 of P32816
1jq5A Bacillus stearothermophilus glycerol dehydrogenase complex with NAD+ (see paper)
39% identity, 92% coverage: 22:387/398 of query aligns to 2:366/366 of 1jq5A
1jqaA Bacillus stearothermophilus glycerol dehydrogenase complex with glycerol (see paper)
39% identity, 92% coverage: 22:387/398 of query aligns to 1:361/361 of 1jqaA
5xn8A Structure of glycerol dehydrogenase crystallised as a contaminant
41% identity, 90% coverage: 24:381/398 of query aligns to 3:359/365 of 5xn8A
1ta9B Crystal structure of glycerol dehydrogenase from schizosaccharomyces pombe
35% identity, 92% coverage: 24:389/398 of query aligns to 8:373/394 of 1ta9B
O13702 Glycerol dehydrogenase 1; GDH; GLDH; EC 1.1.1.6 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
35% identity, 92% coverage: 24:389/398 of query aligns to 64:429/450 of O13702
3uhjA Crystal structure of a probable glycerol dehydrogenase from sinorhizobium meliloti 1021
37% identity, 88% coverage: 24:375/398 of query aligns to 3:348/357 of 3uhjA
4rgqB Crystal structure of the methanocaldococcus jannaschii g1pdh with NADPH and dhap (see paper)
41% identity, 26% coverage: 93:197/398 of query aligns to 53:150/333 of 4rgqB
Sites not aligning to the query:
4rgvA Crystal structure of the methanocaldococcus jannaschii g1pdh (see paper)
42% identity, 26% coverage: 93:197/398 of query aligns to 52:145/328 of 4rgvA
Sites not aligning to the query:
Q9YER2 Glycerol-1-phosphate dehydrogenase [NAD(P)+]; G1P dehydrogenase; G1PDH; Gro1PDH; Enantiomeric glycerophosphate synthase; sn-glycerol-1-phosphate dehydrogenase; EC 1.1.1.261 from Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) (see paper)
25% identity, 80% coverage: 29:347/398 of query aligns to 11:320/352 of Q9YER2
3ce9A Crystal structure of glycerol dehydrogenase (np_348253.1) from clostridium acetobutylicum at 2.37 a resolution
22% identity, 81% coverage: 35:356/398 of query aligns to 13:319/349 of 3ce9A
P31005 NAD-dependent methanol dehydrogenase; MDH; MEDH; Type 3 alcohol dehydrogenase; EC 1.1.1.244 from Bacillus methanolicus (see 3 papers)
25% identity, 72% coverage: 26:311/398 of query aligns to 5:308/381 of P31005
Sites not aligning to the query:
5fb3F Structure of glycerophosphate dehydrogenase in complex with NADPH (see paper)
26% identity, 61% coverage: 95:338/398 of query aligns to 59:296/337 of 5fb3F
Sites not aligning to the query:
>Synpcc7942_1653 FitnessBrowser__SynE:Synpcc7942_1653
MEVSTGYLPQAVFAPADQGHPAPRVFISPQRYIQGRGVLRSVGRYLSLLQAKRAGLLMSQ
RSSRNEGDLLLAGLRSAGVDAVVSTFQGECTTDEITAHTTAFSKERIDCVIAAGGGKCID
TGKAIAFRLGIPVVVVPTLASNDAPCSALSVLYSPEGISQGVEFYPNSPAIVVVDTDIIA
AAPERYLVAGMGDAMATWYEASVCLRNPAAVTTVGARPTLAACAIGEVCAHTLFQEGCAA
AAAVASKTVNDALESVVEANTLLSGLGFESGGLAGAHAVAQSYTAIPHVRANYLHGEMVA
MGTLAQLMMESRPKEATRVAEFFAAVGLPIHLGQLSLSSSDTQALEIVSEASLGFPFVGN
MPMKITPEFVKSAILDAHHLGLSISEQIGDSAYRHLQG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory