Comparing Synpcc7942_2236 FitnessBrowser__SynE:Synpcc7942_2236 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P0AAH4 Putrescine export system ATP-binding protein SapD from Escherichia coli (strain K12) (see paper)
36% identity, 53% coverage: 4:298/554 of query aligns to 2:302/330 of P0AAH4
7z15I E. Coli c-p lyase bound to a phnk/phnl dual abc dimer and adp + pi (see paper)
38% identity, 45% coverage: 298:548/554 of query aligns to 1:247/253 of 7z15I
7z18I E. Coli c-p lyase bound to a phnk abc dimer and atp (see paper)
38% identity, 45% coverage: 298:548/554 of query aligns to 1:247/250 of 7z18I
Q8RDH4 Dipeptide transport ATP-binding protein DppD; EC 7.4.2.9 from Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis) (see paper)
36% identity, 46% coverage: 16:268/554 of query aligns to 19:262/326 of Q8RDH4
Sites not aligning to the query:
4fwiB Crystal structure of the nucleotide-binding domain of a dipeptide abc transporter (see paper)
37% identity, 44% coverage: 16:261/554 of query aligns to 18:254/310 of 4fwiB
Sites not aligning to the query:
7z16I E. Coli c-p lyase bound to phnk/phnl dual abc dimer with amppnp and phnk e171q mutation (see paper)
37% identity, 45% coverage: 298:548/554 of query aligns to 1:247/250 of 7z16I
P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 3 papers)
35% identity, 44% coverage: 300:545/554 of query aligns to 1:241/343 of P30750
Sites not aligning to the query:
6cvlD Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
34% identity, 44% coverage: 300:545/554 of query aligns to 2:242/344 of 6cvlD
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form (see paper)
34% identity, 44% coverage: 300:545/554 of query aligns to 2:242/344 of 3tuzC
Sites not aligning to the query:
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form (see paper)
34% identity, 44% coverage: 300:545/554 of query aligns to 2:242/344 of 3tuiC
P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 3 papers)
36% identity, 48% coverage: 283:548/554 of query aligns to 2:251/378 of P69874
Sites not aligning to the query:
4ymuJ Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
32% identity, 42% coverage: 316:548/554 of query aligns to 13:239/240 of 4ymuJ
Sites not aligning to the query:
4u00A Crystal structure of ttha1159 in complex with adp (see paper)
36% identity, 47% coverage: 4:261/554 of query aligns to 1:236/241 of 4u00A
3c4jA Abc protein artp in complex with atp-gamma-s
32% identity, 45% coverage: 300:548/554 of query aligns to 3:241/242 of 3c4jA
3c41J Abc protein artp in complex with amp-pnp/mg2+
32% identity, 45% coverage: 300:548/554 of query aligns to 3:241/242 of 3c41J
2olkA Abc protein artp in complex with adp-beta-s
32% identity, 45% coverage: 300:548/554 of query aligns to 3:241/242 of 2olkA
2oljA Abc protein artp in complex with adp/mg2+
32% identity, 45% coverage: 300:548/554 of query aligns to 3:241/242 of 2oljA
1vciA Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
35% identity, 42% coverage: 313:547/554 of query aligns to 15:231/353 of 1vciA
2d62A Crystal structure of multiple sugar binding transport atp- binding protein
33% identity, 42% coverage: 319:549/554 of query aligns to 21:247/375 of 2d62A
1g291 Malk (see paper)
33% identity, 42% coverage: 319:549/554 of query aligns to 18:244/372 of 1g291
Sites not aligning to the query:
>Synpcc7942_2236 FitnessBrowser__SynE:Synpcc7942_2236
MADPLLEIRQLQICFGEAIALQGLDLVVQPGESVGIVGESGSGKSVACLAIPGLLPKTAR
CSGQIAFRSVAGQSSRDLLTLPERELRQLRGDRLGFIFQEPLSSLNPVFSAGFQLLEAIQ
QHLPLSQAEAQQRVIALLQEVQLIREPSQAAQILRRYPHQLSGGQRQRLMIAIALAANPD
LLLADEPTTALDATVQASVLQLLRRLQQQRQMAMIFVSHDLGVIAEVADRVVVLYRGQVV
EQGRVADVLNSPQHPYTQGLVACRPQINPRSCYLPTVADFLEGQTEPRSLPPRSPATQPL
LQVEQLGITYRGRSTAFQAVQNLSFTLPAGLTLGLVGESGCGKSSLARCLVGLVPASEGQ
IWLDQQPLDLRSSRDRQRLRQTVQMVFQDPAAALDPRWTVGSAILEPLRIKQPRRDRTAD
QRLLKQWLQRVDLPTDIGDRYPHEFSGGQRQRICIARALIGQPRLLICDESVSALDVSVQ
AQILNLLKQLQAELGLTYLFISHDLAVVRYMSDRILVMNQGQLEEDSPTEQLFQRPQSDY
TRRLIAAIPGEVAA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory