SitesBLAST
Comparing WP_011385301.1 NCBI__GCF_000009985.1:WP_011385301.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8c0zE Cryoem structure of a tungsten-containing aldehyde oxidoreductase from aromatoleum aromaticum (see paper)
49% identity, 99% coverage: 4:414/416 of query aligns to 2:417/424 of 8c0zE
6pfzA Structure of a NAD-dependent persulfide reductase from a. Fulgidus (see paper)
28% identity, 91% coverage: 21:398/416 of query aligns to 19:423/541 of 6pfzA
- active site: V37 (≠ P39), C42 (≠ M44)
- binding calcium ion: D306 (≠ P295), T332 (≠ M321)
- binding coenzyme a: R21 (≠ H23), S38 (≠ P40), G40 (≠ S42), C42 (≠ M44), K76 (vs. gap), R313 (= R302)
- binding flavin-adenine dinucleotide: E32 (≠ C34), A33 (≠ G35), R41 (= R43), C42 (≠ M44), A86 (= A81), A115 (= A106), T116 (= T107), G117 (= G108), L136 (≠ C127), G286 (= G275), D287 (= D276), P303 (≠ A292), F304 (≠ I293), G305 (≠ Q294)
Sites not aligning to the query:
6tukB Crystal structure of fdr9 (see paper)
35% identity, 66% coverage: 3:278/416 of query aligns to 2:262/393 of 6tukB
- binding flavin-adenine dinucleotide: V7 (= V8), G8 (= G9), G9 (= G10), G10 (= G11), A12 (= A13), A34 (≠ G35), E35 (= E36), R42 (= R43), P43 (≠ M44), K47 (≠ Y48), A75 (≠ V80), A76 (= A81), T102 (= T107), G103 (= G108), V118 (≠ C127), R119 (≠ W128), G259 (= G275), D260 (= D276)
Sites not aligning to the query:
3cgeA Pyridine nucleotide complexes with bacillus anthracis coenzyme a- disulfide reductase: a structural analysis of dual NAD(p)h specificity (see paper)
30% identity, 78% coverage: 4:329/416 of query aligns to 2:335/444 of 3cgeA
- active site: A10 (≠ P12), Y37 (≠ P39), Q41 (≠ R43), C42 (≠ M44), N304 (≠ V298)
- binding coenzyme a: M17 (vs. gap), R21 (= R22), S38 (≠ P40), C42 (≠ M44), R61 (≠ K63), N304 (≠ V298), R308 (= R302)
- binding flavin-adenine dinucleotide: I6 (≠ V8), D9 (≠ G11), A10 (≠ P12), A11 (= A13), L31 (= L32), E32 (≠ V33), K33 (≠ C34), Q41 (≠ R43), C42 (≠ M44), V80 (vs. gap), T112 (= T107), G113 (= G108), G281 (= G275), D282 (= D276), I299 (= I293), G300 (≠ Q294), A303 (= A297)
- binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate: I156 (≠ L149), G157 (= G150), A160 (≠ F153), I161 (≠ V154), E164 (≠ I157), E180 (≠ A175), R181 (≠ S176), N182 (≠ G177), T187 (≠ S182), V242 (≠ T238), G243 (= G239), P298 (≠ A292), I299 (= I293)
Sites not aligning to the query:
3cgdA Pyridine nucleotide complexes with bacillus anthracis coenzyme a- disulfide reductase: a structural analysis of dual NAD(p)h specificity (see paper)
30% identity, 78% coverage: 4:329/416 of query aligns to 2:335/444 of 3cgdA
- active site: A10 (≠ P12), Y37 (≠ P39), Q41 (≠ R43), C42 (≠ M44), N304 (≠ V298)
- binding coenzyme a: M17 (vs. gap), Q18 (≠ E19), R21 (= R22), S38 (≠ P40), Y39 (= Y41), C42 (≠ M44), R61 (≠ K63), N304 (≠ V298), R308 (= R302)
- binding flavin-adenine dinucleotide: I6 (≠ V8), G7 (= G9), D9 (≠ G11), A10 (≠ P12), A11 (= A13), L31 (= L32), E32 (≠ V33), K33 (≠ C34), Q41 (≠ R43), C42 (≠ M44), V80 (vs. gap), A111 (= A106), T112 (= T107), G281 (= G275), D282 (= D276), I299 (= I293), G300 (≠ Q294), A303 (= A297)
- binding nicotinamide-adenine-dinucleotide: I156 (≠ L149), G157 (= G150), G159 (= G152), A160 (≠ F153), I161 (≠ V154), E164 (≠ I157), E180 (≠ A175), R181 (≠ S176), V242 (≠ T238), G243 (= G239), P298 (≠ A292), I299 (= I293)
Sites not aligning to the query:
3cgbA Pyridine nucleotide complexes with bacillus anthracis coenzyme a- disulfide reductase: a structural analysis of dual NAD(p)h specificity (see paper)
30% identity, 78% coverage: 4:329/416 of query aligns to 2:335/444 of 3cgbA
- active site: A10 (≠ P12), Y37 (≠ P39), Q41 (≠ R43), C42 (≠ M44), N304 (≠ V298)
- binding coenzyme a: D9 (≠ G11), A10 (≠ P12), M17 (vs. gap), R21 (= R22), S38 (≠ P40), Y39 (= Y41), C42 (≠ M44), R61 (≠ K63), N304 (≠ V298), R308 (= R302)
- binding flavin-adenine dinucleotide: I6 (≠ V8), G7 (= G9), D9 (≠ G11), A10 (≠ P12), A11 (= A13), E32 (≠ V33), K33 (≠ C34), Q41 (≠ R43), C42 (≠ M44), V80 (vs. gap), T112 (= T107), L132 (≠ C127), I161 (≠ V154), G281 (= G275), D282 (= D276), I299 (= I293), G300 (≠ Q294), A303 (= A297)
Sites not aligning to the query:
4h4wA Crystal structure of ferredoxin reductase, bpha4 e175c/t176r/q177g mutant (reduced form)
30% identity, 91% coverage: 6:385/416 of query aligns to 6:376/399 of 4h4wA
- active site: L12 (≠ P12), R43 (= R43), P44 (≠ M44), Q290 (≠ V298)
- binding flavin-adenine dinucleotide: G11 (= G11), A13 (= A13), D35 (≠ G35), R43 (= R43), P44 (≠ M44), A77 (vs. gap), T104 (= T107), G105 (= G108), R125 (≠ W128), I151 (≠ V154), E154 (≠ I157), G267 (= G275), D268 (= D276), T285 (≠ I293), W286 (≠ Q294), A289 (= A297), W315 (≠ L324)
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G148 (≠ A151), I151 (≠ V154), R171 (≠ G174), S177 (≠ R181), R178 (≠ S182), G229 (= G237), I230 (≠ T238), G231 (= G239)
2yvjA Crystal structure of the ferredoxin-ferredoxin reductase (bpha3- bpha4)complex (see paper)
30% identity, 91% coverage: 6:385/416 of query aligns to 7:377/402 of 2yvjA
- active site: L13 (≠ P12), R44 (= R43), P45 (≠ M44), Q291 (≠ V298)
- binding flavin-adenine dinucleotide: G10 (= G9), G12 (= G11), G35 (≠ C34), D36 (≠ G35), E37 (= E36), R44 (= R43), P45 (≠ M44), A78 (vs. gap), T105 (= T107), G106 (= G108), R126 (≠ W128), G268 (= G275), D269 (= D276), T286 (≠ I293), W287 (≠ Q294), A290 (= A297), W316 (≠ L324)
- binding 1,4-dihydronicotinamide adenine dinucleotide: V147 (≠ L149), G148 (= G150), G149 (≠ A151), G150 (= G152), I152 (≠ V154), V170 (≠ C173), E171 (≠ G174), T172 (≠ A175), R179 (≠ S182), G230 (= G237), I231 (≠ T238), G232 (= G239), V233 (= V240), E285 (≠ A292)
1f3pA Ferredoxin reductase (bpha4)-nadh complex (see paper)
30% identity, 91% coverage: 6:385/416 of query aligns to 7:377/401 of 1f3pA
- active site: L13 (≠ P12), R44 (= R43), P45 (≠ M44), Q291 (≠ V298)
- binding flavin-adenine dinucleotide: A14 (= A13), V34 (= V33), D36 (≠ G35), E37 (= E36), R44 (= R43), P45 (≠ M44), A78 (vs. gap), T105 (= T107), G106 (= G108), R126 (≠ W128), G268 (= G275), D269 (= D276), E285 (≠ A292), T286 (≠ I293), W287 (≠ Q294), A290 (= A297), W316 (≠ L324)
- binding nicotinamide-adenine-dinucleotide: V147 (≠ L149), G148 (= G150), G150 (= G152), V151 (≠ F153), I152 (≠ V154), E155 (≠ I157), E171 (≠ G174), T172 (≠ A175), R179 (≠ S182), G230 (= G237), I231 (≠ T238), G232 (= G239), V233 (= V240), E285 (≠ A292), W316 (≠ L324), S317 (≠ E325)
2gr2A Crystal structure of ferredoxin reductase, bpha4 (oxidized form)
30% identity, 91% coverage: 6:385/416 of query aligns to 6:376/401 of 2gr2A
- active site: L12 (≠ P12), R43 (= R43), P44 (≠ M44), Q290 (≠ V298)
- binding adenosine-5-diphosphoribose: R109 (vs. gap), V146 (≠ L149), G147 (= G150), G149 (= G152), V150 (≠ F153), I151 (≠ V154), E170 (≠ G174), T171 (≠ A175), R178 (≠ S182), G229 (= G237), I230 (≠ T238), G231 (= G239), E284 (≠ A292)
- binding flavin-adenine dinucleotide: G11 (= G11), A13 (= A13), D35 (≠ G35), E36 (= E36), R43 (= R43), P44 (≠ M44), K48 (= K63), A77 (vs. gap), T104 (= T107), G105 (= G108), R125 (≠ W128), G267 (= G275), D268 (= D276), T285 (≠ I293), W286 (≠ Q294), A289 (= A297), W315 (≠ L324)
2gr0A Crystal structure of ferredoxin reductase, bpha4 (oxidized form, NAD+ complex) (see paper)
30% identity, 91% coverage: 6:385/416 of query aligns to 6:376/401 of 2gr0A
- active site: L12 (≠ P12), R43 (= R43), P44 (≠ M44), Q290 (≠ V298)
- binding adenosine-5'-diphosphate: V146 (≠ L149), G147 (= G150), G149 (= G152), I151 (≠ V154), E170 (≠ G174), T171 (≠ A175), R178 (≠ S182), G229 (= G237), I230 (≠ T238), G231 (= G239)
- binding flavin-adenine dinucleotide: G11 (= G11), A13 (= A13), D35 (≠ G35), E36 (= E36), R43 (= R43), P44 (≠ M44), K48 (= K63), T76 (vs. gap), A77 (vs. gap), T104 (=