SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing WP_012465627.1 NCBI__GCF_000020465.1:WP_012465627.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 20 (the maximum) hits to proteins with known functional sites (download)

D4GSF3 SAMP-activating enzyme E1; Ubiquitin-like activating enzyme of archaea; Ubl-activating enzyme; EC 2.7.7.- from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
42% identity, 99% coverage: 1:251/253 of query aligns to 3:250/270 of D4GSF3

query
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D4GSF3

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C188 (≠ A186) mutation to S: Loss of activity since this mutant is not able to complement a ubaA deletion in trans to restore sampylation and tRNA thiolation.

O59954 Adenylyltransferase and sulfurtransferase uba4; Common component for nitrate reductase and xanthine dehydrogenase protein F; Ubiquitin-like protein activator 4; EC 2.7.7.80; EC 2.8.1.11 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
38% identity, 98% coverage: 3:249/253 of query aligns to 61:318/482 of O59954

query
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O59954

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G82 (= G24) mutation to D: In cnxF21ts and cnxF24ts; temperature-sensitive mutant. Impairs molybdopterin biosynthesis.
G100 (= G42) mutation to S: In cnxF1285; impairs molybdopterin biosynthesis.
R130 (= R72) mutation to Q: In cnxF200; impairs molybdopterin biosynthesis.
C185 (≠ A127) mutation to Y: In cnxF472; impairs molybdopterin biosynthesis.
E215 (≠ Y157) mutation to K: In cnxF119; impairs molybdopterin biosynthesis.
G264 (= G200) mutation to S: In cnxF142ts; temperature-sensitive mutant. Impairs molybdopterin biosynthesis.

Q72J02 Sulfur carrier protein adenylyltransferase; E1-like protein TtuC; Sulfur carrier protein MoaD adenylyltransferase; Sulfur carrier protein ThiS adenylyltransferase; Sulfur carrier protein TtuB adenylyltransferase; tRNA two-thiouridine-synthesizing protein C; EC 2.7.7.80; EC 2.7.7.73; EC 2.7.7.- from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see paper)
39% identity, 100% coverage: 1:252/253 of query aligns to 1:255/271 of Q72J02

query
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Q72J02

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C192 (≠ T189) modified: Glycyl cysteine thioester (Cys-Gly) (interchain with G-Cter in TtuB); mutation to S: Not able to form a thioester complex with TtuB.

Sites not aligning to the query:

268 C→S: Still able to form a thioester complex with TtuB.

P12282 Molybdopterin-synthase adenylyltransferase; MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase; Sulfur carrier protein MoaD adenylyltransferase; EC 2.7.7.80 from Escherichia coli (strain K12) (see 2 papers)
38% identity, 98% coverage: 3:251/253 of query aligns to 4:249/249 of P12282

query
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P12282

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R14 (= R13) mutation R->A,K: No effect.; mutation to A: No activity; when associated with A-73.
C44 (≠ S43) mutation to A: No effect.
R73 (= R72) mutation to A: No effect. No activity; when associated with A-14.; mutation to K: Substantially reduced activity.
C128 (≠ A127) mutation to A: No effect.; mutation to Y: No activity.
D130 (= D129) mutation to A: No activity.; mutation to E: Substantially reduced activity.
C142 (= C141) mutation to A: No effect.
C172 (= C170) mutation to A: No zinc bound and no enzyme activity.
C175 (= C173) mutation to A: No zinc bound and no enzyme activity.
C187 (≠ T189) mutation to A: No effect.
C231 (≠ M233) mutation to A: No effect.
C244 (= C246) mutation to A: No zinc bound and almost no enzyme activity.
C247 (= C249) mutation to A: No zinc bound and almost no enzyme activity.

1jwbB Structure of the covalent acyl-adenylate form of the moeb-moad protein complex (see paper)
37% identity, 98% coverage: 3:250/253 of query aligns to 3:240/240 of 1jwbB

query
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1jwbB

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V

I

L

D

D

A
x
C

T
|
T

D
|
D

S
x
N

F

V

R

A

A
x
V

K

R

F

N

L

Q

I

L

A

N

K

A

T

G

C

C

H

F

R

A

E

A

E

K

K

V

P

P

Y

L

S

V

H

S

A

G

G

A

I

A

T

I

S

R

Y

M

Y

E

G

G

H

Q

-

I

-

T

T

V

I

F

T

T

V

Y

Q

Q

P

D

G

G

K

E

T

P

A

-

C
|
C

Y

Y

N

R

C

C

I

L

F

-

H

-

E

-

T

-

E

-

P

-

A

-

E

-

A

-

D

-

A

S

H

R

L

L

T

F

V

G

P

E

A

A

G

G

P

V

L

M

G

A

P

P

L

L

P

I

G

G

I

V

I

I

G

G

S

S

I

L

Q

Q

A

A

A

M

E

E

A

A

L

I

K

K

H

M

I

L

L

A

S

G

I

Y

G

G

K

K

G

P

L

A

H

S

N

G

T

K

L

I

L

V

S

M

L

Y

D

D

L

A

L

M

T

T

M

C

T

Q

F

F

R

R

S

E

I

M

P

K

V

L

N

M

P

R

D

N

P

P

N

G

C
|
C

P

E

I

V

C
|
C

G

G

active site: R13 (= R13), D129 (= D129)
binding adenosine monophosphate: G37 (= G37), G39 (= G39), G40 (= G40), D61 (= D61), F62 (≠ G62), K85 (= K85), L108 (vs. gap), C127 (≠ A127), T128 (= T128), D129 (= D129), N130 (≠ S130), V133 (≠ A133)
binding zinc ion: C171 (= C170), C236 (= C246), C239 (= C249)

1jw9B Structure of the native moeb-moad protein complex (see paper)
37% identity, 98% coverage: 3:250/253 of query aligns to 3:240/240 of 1jw9B

query
sites
1jw9B

L

L

N

S

D

D

E

Q

Q

E

R

M

K

L

R

R

F

Y

T

N

R
|
R

H

Q

L

I

S

I

M

L

D

R

E

G

I

F

G

D

E

F

K

D

G

G

Q

Q

E

E

K

A

L

L

L

K

Q

D

A

S

K

R

V

V

L

L

I

I

V

V

G

G

A

L

G

G

L

L

G

G

S

C

P

A

A

A

A

S

F

Q

Y

Y

L

L

A

A

A

S

A

A

G

G

I

V

G

G

T

N

L

L

G

T

L

L

A

L

D

D

G

F

D

D

R

T

V

V

D

S

L

L

S

S

N

N

L

L

Q

Q

R

R

Q

Q

I

T

L

L

H

H

T

S

T

D

A

A

S

T

A

V

G

G

T

Q

P

P

K

K

V

V

S

E

S

S

A

A

A

R

E

D

R

A

I

L

H

T

A

R

L

I

N

N

P

P

A

-

T

-

R

H

L

I

A

A

L

I

H

T

P

P

F

V

H

N

-

A

-

L

L

L

D

D

E

D

K

A

N

E

A

L

E

A

A

A

L

L

I

I

A

A

R

E

Y

H

D

D

F

L

V

V

I

L

D

D

A

C

T

T

D
|
D

S

N

F

V

R

A

A

V

K

R

F

N

L

Q

I

L

A

N

K

A

T

G

C

C

H

F

R

A

E

A

E

K

K

V

P

P

Y

L

S

V

H

S

A

G

G

A

I

A

T

I

S

R

Y

M

Y

E

G

G

H

Q

-

I

-

T

T

V

I

F

T

T

V

Y

Q

Q

P

D

G

G

K

E

T

P

A

-

C
|
C

Y

Y

N

R

C

C

I

L

F

-

H

-

E

-

T

-

E

-

P

-

A

-

E

-

A

-

D

-

A

S

H

R

L

L

T

F

V

G

P

E

A

A

G

G

P

V

L

M

G

A

P

P

L

L

P

I

G

G

I

V

I

I

G

G

S

S

I

L

Q

Q

A

A

A

M

E

E

A

A

L

I

K

K

H

M

I

L

L

A

S

G

I

Y

G

G

K

K

G

P

L

A

H

S

N

G

T

K

L

I

L

V

S

M

L

Y

D

D

L

A

L

M

T

T

M

C

T

Q

F

F

R

R

S

E

I

M

P

K

V

L

N

M

P

R

D

N

P

P

N

G

C
|
C

P

E

I

V

C
|
C

G

G

active site: R13 (= R13), D129 (= D129)
binding zinc ion: C171 (= C170), C236 (= C246), C239 (= C249)

Q9VLJ8 Adenylyltransferase and sulfurtransferase MOCS3; Molybdenum cofactor synthesis protein 3; Ubiquitin activating enzyme 4; EC 2.7.7.80; EC 2.8.1.11 from Drosophila melanogaster (Fruit fly) (see paper)
38% identity, 99% coverage: 3:252/253 of query aligns to 64:312/453 of Q9VLJ8

query
sites
Q9VLJ8

L

L

N

T

D

N

E

D

Q

D

R

I

K

A

R

R

F

Y

T

S

R

R

H

Q

L

L

S

I

M

L

D

P

E

D

I

F

G

G

E

V

K

Q

G

G

Q

Q

E

L

K

K

L

L

L

K

Q

N

A

S

K

S

V

V

L

L

I

I

V

V

G

G

A

L

G

G

L

L

G

G

S

C

P

P

A

A

F

Q

Y

Y

L

L

A

A

G

G

I

C

G

G

T

H

L

L

G

G

L

L

A

V

D

D

G

Y

D

D

R

E

V

V

D

E

L

R

S

S

N

N

L

F

Q

H

R

R

Q

Q

I

I

L

L

H

H

T

S

T

E

A

D

S

R

A

C

G

G

T

M

P

S

K

K

V

A

S

E

S

S

A

A

A

R

E

I

R

A

I

L

H

L

A

E

L

L

N

N

P

P

A

H

T

C

R

E

L

I

A

Q

L

C

H

H

P

S

F

R

H

M

L

L

D

Y

E

P

K

H

N

N

A

A

E

M

A

H

L

I

I

I

A

R

R

G

Y

Y

D

D

F

V

V

V

I

L

D

D

A

C

T

T

D

D

S

N

F

V

R

P

A

T

K

R

F

Y

L

L

I

L

A

S

K

D

T

A

C

C

H

V

R

M

E

L

E

S

K

K

P

P

Y

L

S

V

H

S

A

G

G

S

I

A

T

L

S

K

Y

M

Y

D

G

G

H

Q

T

L

I

T

T

V

V

Y

Q

N

P

Y

G

A

K

N

T

G

A

P

C

C

Y

Y

N

R

C

C

I

I

F

F

H

-

E

P

T

V

E

P

P

P

A

P

E

E

A

A

D

V

A

T

H

N

L

C

T

G

V

-

P

D

A

G

G

G

P

V

L

L

G

G

P

A

L

V

P

T

G

G

I

T

I

I

G

G

S

A

I

M

Q

Q

A

A

A

L

E

E

A

A

L

I

K

K

H

V

I

I

L

V

S

G

I

M

G

G

K

D

G

V

L

L

H

A

N

G

T

R

L

L

S

I

L

F

D

D

L

G

T

S

M

G

T

V

F

F

R

R

S

N

I

I

P

R

V

I

N

R

P

S

D

K

-

R

P

P

N

N

C

C

P

H

I

M

C

C

G

S

K

A

K

Q

Sites not aligning to the query:

62 modified: Phosphothreonine

6yubB Crystal structure of uba4 from chaetomium thermophilum (see paper)
36% identity, 85% coverage: 2:216/253 of query aligns to 6:214/289 of 6yubB

query
sites
6yubB

A

S

L

L

N

S

D

K

E

E

Q

E

R

I

K

E

R

R

F

Y

T

S

R

R

H

Q

L

M

S

I

M

V

D

P

E

G

I

M

G

G

E

K

K

E

G

G

Q

Q

E

L

K

R

L

L

L

M

Q

N

A

A

K

K

V

V

L

L

I

I

V

I

G

G

A

A

G

G

L

L

G

G

S

C

P

P

A

A

F

Q

Y

Y

L

L

A

A

A

G

A

A

G

G

I

V

G

G

T

T

L

I

G

G

L

I

A

V

D

D

G

G

D

D

R

S

V

V

D

E

L

T

S

S

N

N

L

L

Q

H

R

R

Q

Q

I

V

L

A

H

H

T

A

T

T

A

K

S

R

A

V

G

G

T

M

P

L

K

K

V

V

S

D

S

S

A

L

A

I

E

T

R

H

I

L

H

I

A

E

L

I

N

N

P

P

A

L

T

P

R

V

L

Y

A

V

L

P

H

Y

P

R

F

F

H

D

L

L

D

T

E

P

K

Q

N

N

A

A

E

A

A

Q

L

I

I

I

A

K

R

P

Y

W

D

D

F

V

V

I

I

L

D

D

A

C

T

T

D

D

S

N

F

P

R

A

A

T

K

R

F

Y

L

L

I

I

A

S

K

D

T

V

C

C

H

V

R

L

E

L

E

G

K

K

P

P

Y

L

S

V

H

S

A

A

G

A

I

S

T

V

S

Q

Y

K

Y

S

G

G

H

Q

T

L

I

I

-

V

-

L

-

N

-

C

-

P

-

T

-

P

-

Q

-

G

T

V

V

V

Q

N

P

K

G

K

K

A

T

A

A

P

C
|
C

Y

Y

N

R

C
|
C

I

C

F

F

H

K

E

-

T

-

E

-

P

-

A

-

E

-

A

-

D

-

A

-

H

-

L

-

T

-

V

-

P

-

A

-

G

G

P

I

L

M

G

G

P

P

L

V

P

V

G

G

I

M

G

G

S

V

I

A

Q

Q

A

A

A

G

E

E

A

A

L

I

K

K

H

I

I

L

L

V

S

S

binding zinc ion: C184 (= C170), C187 (= C173)

Sites not aligning to the query:

binding zinc ion: 265

6yubA Crystal structure of uba4 from chaetomium thermophilum (see paper)
36% identity, 85% coverage: 2:216/253 of query aligns to 5:215/423 of 6yubA

query
sites
6yubA

A

S

L

L

N

S

D

K

E

E

Q

E

R

I

K

E

R

R

F

Y

T

S

R

R

H

Q

L

M

S

I

M

V

D

P

E

G

I

M

G

G

E

K

K

E

G

G

Q

Q

E

L

K

R

L

L

L

M

Q

N

A

A

K

K

V

V

L

L

I

I

V

I

G

G

A

A

G

G

L

L

G

G

S

C

P

P

A

A

F

Q

Y

Y

L

L

A

A

A

G

A

A

G

G

I

V

G

G

T

T

L

I

G

G

L

I

A

V

D

D

G

G

D

D

R

S

V

V

D

E

L

T

S

S

N

N

L

L

Q

H

R

R

Q

Q

I

V

L

A

H

H

T

A

T

T

A

K

S

R

A

V

G

G

T

M

P

L

K

K

V

V

S

D

S

S

A

L

A

I

E

T

R

H

I

L

H

I

A

E

L

I

N

N

P

P

A

L

T

P

R

V

L

Y

A

V

L

P

H

Y

P

R

F

F

H

D

L

L

D

T

E

P

K

Q

N

N

A

A

E

A

A

Q

L

I

I

I

A

K

R

P

Y

W

D

D

F

V

V

I

I

L

D

D

A

C

T

T

D

D

S

N

F

P

R

A

A

T

K

R

F

Y

L

L

I

I

A

S

K

D

T

V

C

C

H

V

R

L

E

L

E

G

K

K

P

P

Y

L

S

V

H

S

A

A

G

A

I

S

T

V

S

Q

Y

K

Y

S

G

G

H

Q

T

L

I

I

-

V

-

L

-

N

-

C

-

P

-

T

-

P

-

Q

-

G

T

V

V

V

Q

N

P

K

G

K

K

A

T

A

A

P

C
|
C

Y

Y

N

R

C
|
C

I

C

F

F

H

K

E

K

T

-

E

-

P

-

A

-

E

-

A

-

D

-

A

-

H

-

L

-

T

-

V

-

P

-

A

P

G

G

P

I

L

M

G

G

P

P

L

V

P

V

G

G

I

M

G

G

S

V

I

A

Q

Q

A

A

A

G

E

E

A

A

L

I

K

K

H

I

I

L

L

V

S

S

binding zinc ion: C183 (= C170), C186 (= C173)

Sites not aligning to the query:

binding zinc ion: 266, 269

1zud3 Structure of this-thif protein complex (see paper)
36% identity, 98% coverage: 3:250/253 of query aligns to 1:239/240 of 1zud3

query
sites
1zud3

L

M

N

N

D

D

E

R

Q

D

R

F

K

M

R

R

F

Y

T

S

R
|
R

H

Q

L

I

S
x
L

M

L

D
|
D

E

D

I

I

G

A

E

L

K

D

G

G

Q

Q

E

Q

K

K

L

L

Q

D

A

S

K

Q

V

V

L

L

I

I

V

I

G

G

A

L

G

G

L

L

G

G

S

T

P

P

A

A

F

L

Y

Y

L

L

A

A

A

G

A

A

G

G

I

V

G

G

T

T

L

L

G

V

L

L

A

A

D

D

G

D

D

D

R

D

V

V

D

H

L

L

S

S

N

N

L

L

Q

Q

R

R

Q

Q

I

I

L

L

H

F

T

T

A

E

S

D

A

I

G

D

T

R

P

P

K

K

V

S

S

Q

S

V

A

S

A

Q

E

Q

R

R

I

L

H

T

A

Q

L

L

N

N

P

P

A

D

T

I

R

Q

L

L

A

T

L

A

H

L

P

Q

F

Q

H

R

L

L

D

T

E

G

K

E

N

A

A

L

E

K

A

D

L

A

I

V

A

A

R

R

Y

A

D

D

F

V

V

V

I

L

D

D

A

C

T

T

D
|
D

S

N

F

M

R

A

A

T

K

R

F

Q

L

E

I

I

A

N

K

A

T

A

C

C

H

V

R

A

E

L

E

N

K

T

P

P

Y

L

S

I

H

T

A

A

G

S

I

A

T

V

S

G

Y

F

Y

G

G

G

H

Q

T

L

I

M

T

V

V

L

Q

T

-

P

P

P

G

W

K

E

T

Q

A

G

C
|
C

Y

Y

N

R

C

C

I

L

F

W

H

P

E

D

T

N

-

Q

E

E

P

P

A

T

A

A

E

G

A

V

D

V

A

G

H

P

L

V

T

V

V

G

P

V

A

M

G

-

P

-

L

-

G

-

P

-

L

-

P

-

G

-

I

-

G

G

S

T

I

L

Q

Q

A

A

A

L

E

E

A

A

L

I

K

K

H

-

I

L

L

L

S

S

I

G

G

I

K

E

G

T

L

P

H

A

N

G

T

E

L

L

L

R

S

L

L

F

D

D

L

G

L

K

T

S

M

S

T

Q

F

W

R

R

S

S

I

L

P

A

V

L

N

R

P

R

D

A

P

S

N

G

C
|
C

P

P

I

V

C
|
C

G

G

active site: R11 (= R13), D127 (= D129)
binding calcium ion: L14 (≠ S16), D16 (= D18)
binding zinc ion: C169 (= C170), C235 (= C246), C238 (= C249)

P30138 Sulfur carrier protein ThiS adenylyltransferase; EC 2.7.7.73 from Escherichia coli (strain K12) (see 3 papers)
37% identity, 99% coverage: 3:253/253 of query aligns to 1:247/251 of P30138

query
sites
P30138

L

M

N

N

D

D

E

R

Q

D

R

F

K

M

R

R

F

Y

T

S

R

R

H

Q

L

I

S

L

M

L

D

D

E

D

I

I

G

A

E

L

K

D

G

G

Q

Q

E

Q

K

K

L

L

Q

D

A

S

K

Q

V

V

L

L

I

I

V

I

G

G

A

L

G

G

L

L

G

G

S

T

P

P

A

A

F

L

Y

Y

L

L

A

A

A

G

A

A

G

G

I

V

G

G

T

T

L

L

G

V

L

L

A

A

D

D

G

D

D

D

R

D

V

V

D

H

L

L

S

S

N

N

L

L

Q

Q

R

R

Q

Q

I

I

L

L

H

F

T

T

A

E

S

D

A

I

G

D

T

R

P

P

K

K

V

S

S

Q

S

V

A

S

A

Q

E

Q

R

R

I

L

H

T

A

Q

L

L

N

N

P

P

A

D

T

I

R

Q

L

L

A

T

L

A

H

L

P

Q

F

Q

H

R

L

L

D

T

E

G

K

E

N

A

A

L

E

K

A

D

L

A

I

V

A

A

R

R

Y

A

D

D

F

V

V

V

I

L

D

D

A

C

T

T

D

D

S

N

F

M

R

A

A

T

K

R

F

Q

L

E

I

I

A

N

K

A

T

A

C

C

H

V

R

A

E

L

E

N

K

T

P

P

Y

L

S

I

H

T

A

A

G

S

I

A

T

V

S

G

Y

F

Y

G

G

G

H

Q

T

L

I

M

T

V

V

L

Q

T

-

P

P

P

G

W

K

E

T

Q

A

G

C
|
C

Y

Y

N

R

C
|
C

I

L

F
x
W

H

P

E

D

T

N

-

Q

E

E

P

P

A

E

A

R

E

N

A
x
C

D

R

A

T

H

-

L

-

T

-

V

-

P

-

A

A

G

G

P

V

L

V

G

G

P

P

L

V

P

V

G

G

I

V

I

M

G

G

S

T

I

L

Q

Q

A

A

A

L

E

E

A

A

L

I

K

K

H

-

I

L

L

L

S

S

I

G

G

I

K

E

G

T

L

P

H

A

N

G

T

E

L

L

L

R

S

L

L

F

D

D

L

G

L

K

T

S

M

S

T

Q

F

W

R

R

S

S

I

L

P

A

V

L

N

R

P

R

D

A

P

S

N

G

C
|
C

P

P

I

V

C
|
C

G

G

K

G

K

S

N

N

C169 (= C170) binding Zn(2+)
C172 (= C173) binding Zn(2+)
W174 (≠ F175) mutation to A: No adenylation of ThiS.
C184 (≠ A184) mutation to S: No cross-link formed with ThiS. No effect on ThiS thiocarboxylate formation in vitro. Does not support growth.
C240 (= C246) binding Zn(2+)
C243 (= C249) binding Zn(2+)

1zfnA Structural analysis of escherichia coli thif (see paper)
37% identity, 98% coverage: 3:250/253 of query aligns to 1:244/244 of 1zfnA

query
sites
1zfnA

L

M

N

N

D

D

E

R

Q

D

R

F

K

M

R

R

F

Y

T

S

R
|
R

H

Q

L

I

S

L

M

L

D

D

E

D

I

I

G

A

E

L

K

D

G

G

Q

Q

E

Q

K

K

L

L

Q

D

A

S

K

Q

V

V

L

L

I

I

V
x
I

G
|
G

A

L

G
|
G

L

L

G

G

S

T

P

P

A

A

F

L

Y

Y

L

L

A

A

A

G

A

A

G

G

I

V

G

G

T

T

L

L

G

V

L

L

A

A

D
|
D

G

D

D

D

R

D

V

V

D

H

L

L

S

S

N

N

L

L

Q

Q

R
|
R

Q
|
Q

I

I

L

L

H

F

T

T

A

E

S

D

A

I

G

D

T

R

P

P

K
|
K

V

S

S

Q

S

V

A

S

A

Q

E

Q

R

R

I

L

H

T

A

Q

L

L

N

N

P

P

A

D

T

I

R

Q

L

L

A

T

L

A

H

L

P

Q

F

Q

H

R

L

L

D

T

E

G

K

E

N

A

A

L

E

K

A

D

L

A

I

V

A

A

R

R

Y

A

D

D

F

V

V

V

I

L

D

D

A

C

T
|
T

D
|
D

S

N

F

M

R

A

A
x
T

K

R

F

Q

L

E

I

I

A

N

K

A

T

A

C

C

H

V

R

A

E

L

E

N

K

T

P

P

Y

L

S

I

H

T

A

A

G

S

I

A

T

V

S

G

Y

F

Y

G

G

G

H

Q

T

L

I

M

T

V

V

L

Q

T

-

P

P

P

G

W

K

E

T

Q

A

G

C
|
C

Y

Y

N

R

C
|
C

I

L

F

W

H

P

E

D

T

N

-

Q

E

E

P

P

A

E

A

R

E

N

A

C

D

R

A

T

H

-

L

-

T

-

V

-

P

-

A

A

G

G

P

V

L

V

G

G

P

P

L

V

P

V

G

G

I

V

I

M

G

G

S

T

I

L

Q

Q

A

A

A

L

E

E

A

A

L

I

K

K

H

-

I

L

L

L

S

S

I

G

G

I

K

E

G

T

L

P

H

A

N

G

T

E

L

L

L

R

S

L

L

F

D

D

L

G

L

K

T

S

M

S

T

Q

F

W

R

R

S

S

I

L

P

A

V

L

N

R

P

R

D

A

P

S

N

G

C
|
C

P

P

I

V

C
|
C

G

G

active site: R11 (= R13), D127 (= D129)
binding adenosine-5'-triphosphate: I34 (≠ V36), G35 (= G37), G37 (= G39), G38 (= G40), D59 (= D61), R70 (= R72), Q71 (= Q73), K83 (= K85), T126 (= T128), D127 (= D129), T131 (≠ A133)
binding zinc ion: C169 (= C170), C172 (= C173), C240 (= C246), C243 (= C249)

1jwaB Structure of the atp-bound moeb-moad protein complex (see paper)
36% identity, 94% coverage: 3:240/253 of query aligns to 3:215/217 of 1jwaB

query
sites
1jwaB

L

L

N

S

D

D

E

Q

Q

E

R

M

K

L

R

R

F

Y

T

N

R
|
R

H

Q

L

I

S

I

M

L

D

R

E

G

I

F

G

D

E

F

K

D

G

G

Q

Q

E

E

K

A

L

L

L

K

Q

D

A

S

K

R

V

V

L

L

I

I

V

V

G

G

A

L

G
|
G

L

L

G

G

S

C

P

A

A

A

A

S

F

Q

Y

Y

L

L

A

A

A

S

A

A

G

G

I

V

G

G

T

N

L

L

G

T

L

L

A

L

D
|
D

G
x
F

D

D

R

T

V

V

D

S

L

L

S

S

N

N

L

L

Q

Q

R
|
R

Q

Q

I

T

L

L

H

H

T

S

T

D

A

A

S

T

A

V

G

G

T

Q

P

P

K
|
K

V

V

S

E

S

S

A

A

A

R

E

D

R

A

I

L

H

T

A

R

L

I

N

N

P

P

A

-

T

-

R

H

L

I

A

A

L

I

H

T

P

P

F

V

H

N

-

A

-
x
L

L

L

D

D

E

D

K

A

N

E

A

L

E

A

A

A

L

L

I

I

A

A

R

E

Y

H

D

D

F

L

V

V

I

L

D

D

A

C

T

T

D
|
D

S
x
N

F

V

R

A

A
x
V

K

R

F

N

L

Q

I

L

A

N

K

A

T

G

C

C

H

F

R

A

E

A

E

K

K

V

P

P

Y

L

S

V

H

S

A

G

G

A

I

A

T

I

S

R

Y

M

Y

E

G

G

H

Q

T

-

I

I

T

T

V

V

Q

-

P

-

G

-

K

-

T

-

A

-

C

-

Y

-

N

-

C

-

I

-

F

-

H

-

E

-

T

-

E

-

P

-

A

-

E

-

A

-

D

-

A

-

H

-

L

F

T

T

V

Y

P

E

A

A

G

G

P

V

L

M

G

A

P

P

L

L

P

I

G

G

I

V

I

I

G

G

S

S

I

L

Q

Q

A

A

A

M

E

E

A

A

L

I

K

K

H

M

I

L

L

A

S

G

I

Y

G

G

K

K

G

P

L

A

H

S

N

G

T

K

L

I

L

V

S

M

L

Y

D

D

L

A

L

M

T

T

M

C

T

Q

F

F

R

R

S

E

I

M

P

K

V

L

active site: R13 (= R13), D129 (= D129)
binding adenosine-5'-triphosphate: G39 (= G39), G40 (= G40), D61 (= D61), F62 (≠ G62), R72 (= R72), K85 (= K85), L108 (vs. gap), D129 (= D129), N130 (≠ S130), V133 (≠ A133)

P38820 Adenylyltransferase and sulfurtransferase UBA4; Needs CLA4 to survive protein 3; Ubiquitin-like protein activator 4; EC 2.7.7.-; EC 2.8.1.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
37% identity, 85% coverage: 3:217/253 of query aligns to 39:253/440 of P38820

query
sites
P38820

L

L

N

S

D

L

E

E

Q

E

R

Y

K

Q

R

R

F

Y

T

G

R

R

H

Q

L

M

S

I

M

V

D

E

E

E

I

T

G

G

-

G

E

V

K

A

G

G

Q

Q

E

V

K

K

L

L

L

K

Q

N

A

T

K

K

V

V

L

L

I

V

V

V

G

G

A

A

G

G

L

L

G

G

S

C

P

P

A

A

A

L

F

P

Y

Y

L

L

A

A

A

G

A

A

G

G

I

V

G

G

T

Q

L

I

G

G

L

I

A

V

D

D

G

N

D

D

R

V

V

V

D

E

L

T

S

S

N

N

L

L

Q

H

R

R

Q

Q

I

V

L

L

H

H

T

D

T

S

A

S

S

R

A

V

G

G

T

M

P

L

K

K

V

C

S

E

S

S

A

A

A

R

E

Q

R

Y

I

I

H

T

A

K

L

L

N

N

P

P

A

H

T

I

R

N

L

V

A

V

L

T

H

Y

P

P

F

V

H

R

L

L

D

N

E

S

K

S

N

N

A

A

E

F

A

D

L

I

I

F

A

K

R

G

Y

Y

D

N

F

Y

V

I

I

L

D

D

A

C

T

T

D

D

S

S

F

P

R

L

A

T

K

R

F

Y

L

L

I

V

A

S

K

D

T

V

-

A

C

V

H

N

R

L

E

G

E

I

K

T

P

V

Y

V

S

S

H

A

A

S

G

G

I

L

T

G

S

T

Y

E

Y

G

G

Q

H

L

T

T

I

I

T

L

V

N

Q

F

P

N

G

N

K

I

T

G

A

P

C

C

Y

Y

N

R

C

C

I

-

F

F

H

Y

E

P

T

T

E

P

P

P

A

P

E

N

A

A

D

V

A

T

H

S

L
x
C

T

Q

V

-

P

E

A

G

G

G

P

V

L

I

G

G

P

P

L

C

P

I

G

G

I

L

I

V

G

G

S

T

I

M

Q

M

A

A

A

V

E

E

A

T

L

L

K

K

H

L

I

I

L

L

S

G

I

I

C225 (≠ L188) mutation C->A,S: Abolishes adenylyltransferase activity but not sulfurtransferase activity.

Sites not aligning to the query:

397 mutation C->A,S: Abolishes sulfurtransferase activity but not adenylyltransferase activity.

O95396 Adenylyltransferase and sulfurtransferase MOCS3; Molybdenum cofactor synthesis protein 3; Molybdopterin synthase sulfurylase; MPT synthase sulfurylase; EC 2.7.7.80; EC 2.8.1.11 from Homo sapiens (Human) (see 5 papers)
36% identity, 99% coverage: 2:252/253 of query aligns to 54:303/460 of O95396

query
sites
O95396

A

A

L

L

N

S

D

R

E

D

Q

E

R

I

K

L

R

R

F

Y

T

S

R

R

H

Q

L

L

S

V

M

L

D

P

E

E

I

L

G

G

E

V

K

H

G

G

Q

Q

E

L

K

R

L

L

L

G

Q

T

A

A

K

C

V

V

L

L

I

I

V

V

G

G

A

C

G

G

L

L

G

G

S

C

P

P

A

L

A

A

F

Q

Y

Y

L

L

A

A

G

G

I

V

G

G

T

R

L

L

G

G

L

L

A

V

D

D

G

Y

D

D

R

V

V

V

D

E

L

M

S

S

N

N

L

L

Q

A

R

R

Q

Q

I

V

L

L

H

H

T

G

T

E

A

A

S

L

A

A

G

G

T

Q

P

A

K

K

V

A

S

F

S

S

A

A

E

A

R

S

I

L

H

R

A

R

L

L

N

N

P

S

A

A

T

V

R

E

L

C

A

V

L

P

H

Y

P
x
T

F
x
Q

H
x
A

L
|
L

D
x
T

E
x
P

K
x
A

N
x
T

A
|
A

E
x
L

A
x
D

L
|
L

I
x
V

A
x
R

R
|
R

Y
|
Y

D
|
D

F
x
V

V
|
V

I
x
A

D
|
D

A
x
C

T
x
S

D
|
D

S
x
N

F
x
V

R
x
P

A
x
T

K
x
R

F
x
Y

L
|
L

I
x
V

A
x
N

K
x
D

T
x
A

C
|
C

H
x
V

R
x
L

E
x
A

E
x
G

K
x
R

P
|
P

Y
x
L

S
x
V

H
x
S

A
|
A

G
x
S

I
x
A

T
x
L

S
x
R

Y
x
F

Y
x
E

G
|
G

H
x
Q

T
x
I

I
x
T

T
x
V

V
x
Y

Q
x
H

P
x
Y

G
x
D

K
x
G

T
x
G

A
x
P

C
|
C

Y
|
Y

N
x
R

C
|
C

I
|
I

F
|
F

H
x
P

E
x
Q

T
x
P

E
x
P

P
|
P

A
|
A

A
x
E

E
x
T

-
x
V

-
x
T

-
x
N

-
x
C

A

A

D

D

A

G

H

G

L

V

T

L

V

G

P

V

A

V

G

T

P

-

L

-

G

-

P

-

L

-

P

-

G

G

I

V

I

L

G

G

S

C

I

L

Q

Q

A

A

A

L

E

E

A

V

L

L

K

K

H

I

I

A

L

A

S

G

I

L

G

G

K

P

G

S

L

Y

H

S

N

G

T

S

L

L

S

L

L

F

D

D

L

A

L

L

T

R

M

G

T

H

F

F

-

R

R

S

S

I

I

R

P

L

V

R

N

S

P

R

D

R

P

L

N

D

C

C

P

A

I

A

C

C

G

G

K

E

K

R

158:238 (vs. 106:183, 26% identical) Interaction with NFS1
C239 (vs. gap) mutation to A: Impairs sulfurtransferase activity.

Sites not aligning to the query:

316 modified: Disulfide link with 324; C→A: Does not affect sulfurtransferase activity.
324 modified: Disulfide link with 316; C→A: Does not affect sulfurtransferase activity.
365 C→A: Does not affect sulfurtransferase activity.
412 active site, Cysteine persulfide intermediate; for sulfurtransferase activity; modified: Cysteine persulfide; C→A: Abolishes sulfurtransferase activity.
413 K→R: Does not affect sulfurtransferase specificity and activity.
414 L→K: Does not affect sulfurtransferase specificity and activity.
415 G→A: Does not affect sulfurtransferase specificity and activity.
416 N→V: Does not affect sulfurtransferase specificity and activity.
417 D→R: Results in 470-fold increased activity.; D→T: Results in 90-fold increased activity.
458 P→G: Does not affect sulfurtransferase specificity and activity.
460 Y→A: Does not affect sulfurtransferase specificity and activity.

O42939 Ubiquitin-activating enzyme E1-like; Pmt3-activating enzyme subunit 2 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
34% identity, 57% coverage: 31:173/253 of query aligns to 26:169/628 of O42939

query
sites
O42939

A

A

K

K

V

V

L

L

I

L

V

V

G

G

A

A

G

G

L

I

G

G

S

C

P

E

A

L

F

K

Y

N

L

L

A

L

A

M

A

S

G

G

I

V

G

K

T

E

L

V

G

H

L

I

A

I

D

D

G

L

D

D

R

T

V

I

D

D

L

L

S

S

N

N

L

L

Q

N

R

R

Q

Q

I

F

L

L

H

F

T

R

T

K

A

K

S

H

A

V

G

K

T

Q

P

P

K

K

V

A

S

I

S

V

A

A

E

K

R

T

I

A

H

S

A

S

L

F

N

N

P

P

A

N

T

V

R

K

L

L

-

E

A

A

L

Y

H

H

P

A

F

N

H

I

L

K

D

E

E

D

K

R

N

F

A

N

E

V

A

A

L

W

I

F

A

R

R

Q

Y

F

D

D

F

L

V

V

I

F

D

N

A

A

T

L

D

D

S

N

F

L

R

D

A

A

K

R

F

R

L

H

I

V

A

N

K

K

T

Q

C

C

H

L

R

L

E

A

E

S

K

V

P

P

Y

L

S

I

H

E

A

S

G

G

I

T

T

T

S

G

Y

F

Y

L

G

G

H

Q

T

V

I

Q

T

V

V

I

Q

I

P

H

G

G

K

K

T

T

A

E

C

C

Y

Y

N

D

C

C

Sites not aligning to the query:

559 modified: Phosphoserine
563 modified: Phosphoserine

4yedD Tcda (csdl) (see paper)
35% identity, 60% coverage: 1:152/253 of query aligns to 2:152/255 of 4yedD

query
sites
4yedD

M

V

A

V

L

I

N

S

D

D

E

A

Q

W

R

R

K

Q

R

R

F

F

T

G

R

G

H

T

L

A

S

R

M

L

D

-

E

-

I

Y

G

G

E

E

K

K

G

A

Q

L

E

Q

K

L

L

F

L

A

Q

D

A

A

K

H

V

I

L

C

I

V

V

V

G
|
G

A

I

G

G

G
|
G

L

V

G

G

S

S

P

W

A

A

F

E

Y

A

L

L

A

A

A

R

A

T

G

G

I

I

G

G

T

A

L

I

G

T

L

L

A
x
I

D
|
D

G

M

D
|
D

R

D

V

V

D

C

L

V

S

T

N

N

L

T

Q

N

R

R

Q

Q

I

I

L

H

H

A

T

L

T

R

A

D

S

N

A

V

G

G

T

L

P

A

K
|
K

V

A

S

E

S

V

A

M

A

A

E

E

R

R

I

I

H

R

A

Q

L

I

N

N

P

P

A

E

T

C

R

R

L

V

-

T

A

V

L

V

H

D

P

D

F
|
F

H
x
V

L

T

D

P

E

D

K

N

N

V

A

A

E

Q

A

Y

L

M

I

S

A

V

R

G

Y

Y

D

S

F

Y

V

V

I

I

D

D

A

A

T

I

D
|
D

S

S

F

V

R

R

A
x
P

K

K

F

A

L

A

I

L

A

I

K

A

T

Y

C

C

H

R

R

R

E

N

E

K

K

I

P

P

Y

L

S

V

H

T

A

T

G

G

binding adenosine monophosphate: G36 (= G37), G39 (= G40), I59 (≠ A60), D60 (= D61), D62 (= D63), K84 (= K85), F107 (= F107), V108 (≠ H108), D129 (= D129), P133 (≠ A133)

4d79A Crystal structure of e. Coli tRNA n6-threonylcarbamoyladenosine dehydratase, tcda, in complex with atp at 1.768 angstroem resolution (see paper)
35% identity, 60% coverage: 1:152/253 of query aligns to 1:151/243 of 4d79A

query
sites
4d79A

M

V

A

V

L

I

N

S

D

D

E

A

Q

W

R

R

K

Q

R

R

F

F

T

G

R

G

H

T

L

A

S

R

M

L

D

-

E

-

I

Y

G

G

E

E

K

K

G

A

Q

L

E

Q

K

L

L

F

L

A

Q

D

A

A

K

H

V

I

L

C

I

V

V

V

G
|
G

A

I

G
|
G

L

V

G

G

S

S

P

W

A

A

F

E

Y

A

L

L

A

A

A

R

A

T

G

G

I

I

G

G

T

A

L

I

G

T

L

L

A

I

D
|
D

G

M

D

D

R

D

V

V

D

C

L

V

S

T

N

N

L

T

Q

N

R
|
R

Q

Q

I

I

L

H

H

A

T

L

T

R

A

D

S

N

A

V

G

G

T

L

P

A

K
|
K

V

A

S

E

S

V

A

M

A

A

E

E

R

R

I

I

H

R

A

Q

L

I

N

N

P

P

A

E

T

C

R

R

L

V

-

T

A

V

L

V

H

D

P

D

F
|
F

H
x
V

L

T

D

P

E

D

K

N

N

V

A

A

E

Q

A

Y

L

M

I

S

A

V

R

G

Y

Y

D

S

F

Y

V

V

I

I

D

D

A

A

T

I

D
|
D

S

S

F

V

R

R

A
x
P

K

K

F

A

L

A

I

L

A

I

K

A

T

Y

C

C

H

R

R

R

E

N

E

K

K

I

P

P

Y

L

S

V

H

T

A

T

G

G

binding adenosine-5'-triphosphate: G35 (= G37), G37 (= G39), G38 (= G40), D59 (= D61), R70 (= R72), K83 (= K85), F106 (= F107), V107 (≠ H108), D128 (= D129), P132 (≠ A133)

3h9jA Crystal structure of e. Coli mccb + ampcpp + semet mcca (see paper)
26% identity, 98% coverage: 4:250/253 of query aligns to 85:338/339 of 3h9jA

query
sites
3h9jA

N

N

D

S

E

T

Q

E

R

N

K

N

R

R

F

Y

T

S

R

R

H

N

-

F

L

L

S

H

M

Y

D

Q

E

S

I

Y

G

G

E

A

K

N

-

P

-

V

-

L

G

V

Q

Q

E

D

K

K

L

L

L

K

Q

N

A

A

K

K

V

V

L

V

I

I

V

L

G

G

A

C

G
|
G

L

I

G

G

S

N

P

H

A

V

A

S

F

V

Y

I

L

L

A

A

A

T

A

S

G

G

I

I

G

G

T

E

L

I

G

I

L

L

A

I

D
|
D

G

N

D
|
D

R

Q

V

I

D

E

L

N

S

T

N

N

L

L

Q

T

R
|
R

Q

Q

I

V

L

L

H

F

T

S

T

E

A

D

S

D

A

V

G

G

T

K

P

N

K
|
K

V

T

S

E

S

V

A

I

A

K

E

R

R

E

I

L

H

L

A

K

L

R

N

N

P

S

A

E

T

I

R

S

L

V

A

S

L

E

H

I

P

A

F

L

H
x
N

L
x
I

D

N

E

D

K

Y

N

T

A

D

E

L

A

H

L

K

I

V

A

P

R

E

Y

A

D

D

-

I

F

W

V

V

I

V

D

S

A
|
A

T
x
D

D
x
H

S

P

F

F

R

N

A

L

K

I

F

N

L

W

I

V

A

N

K

K

T

Y

C

C

H

V

R

R

E

A

E

N

K

Q

P

P

Y

Y

S

I

H

N

A

A

G

G

I

-

T

-

S

-

Y

-

Y

Y

G

V

H

N

T

D

I

I

T

A

V

V

-

F

-

G

-

P

-

L

-

Y

Q

V

P

P

G

G

K

K

T

T

A

G

C
|
C

Y

Y

N

E

C

C

I

Q

F

K

H

K

E

E

T

N

E

I

P

D

A

H

A

K

E

I

A

K

D

L

A

I

H

N

L

S

T

R

V

F

P

K

A

P

G

A

P

T

L

F

G

A

P

P

L

V

P

N

G

N

I

V

I

A

G

A

S

A

I

L

Q

C

A

A

E

D

A

V

L

I

K

K

H

F

I

I

L

G

S

K

I

Y

G

S

K

E

G

P

L

L

H

S

-

L

N

N

T

K

L
x
R

L

I

S
x
G

L

I

D

W

L

S

L

D

T

E

M

I

T

K

F

I

R

H

S

S

I

Q

P

N

V

M

N

G

P

R

D

S

P

P

N

V

C
|
C

P

S

I

V

C
|
C

G

G

active site: R157 (= R72)
binding diphosphomethylphosphonic acid adenosyl ester: G124 (= G39), G125 (= G40), D146 (= D61), D148 (= D63), R157 (= R72), K170 (= K85), N193 (≠ H108), I194 (≠ L109), A213 (= A127), D214 (≠ T128), H215 (≠ D129)
binding zinc ion: C257 (= C170), C334 (= C246), C337 (= C249)
binding : R313 (≠ L225), G315 (≠ S227)

3h5nA Crystal structure of e. Coli mccb + atp (see paper)
26% identity, 98% coverage: 4:250/253 of query aligns to 85:338/338 of 3h5nA

query
sites
3h5nA

N

N

D

S

E

T

Q

E

R

N

K

N

R

R

F

Y

T

S

R

R

H

N

-

F

L

L

S

H

M

Y

D

Q

E

S

I

Y

G

G

E

A

K

N

-

P

-

V

-

L

G

V

Q

Q

E

D

K

K

L

L

L

K

Q

N

A

A

K

K

V

V

L

V

I

I

V

L

G

G

A

C

G
|
G

G

G

L

I

G

G

S

N

P

H

A

V

A

S

F

V

Y

I

L

L

A

A

A

T

A

S

G

G

I

I

G

G

T

E

L

I

G

I

L

L

A

I

D
|
D

G

N

D

D

R

Q

V

I

D

E

L

N

S

T

N
|
N

L

L

Q

T

R
|
R

Q
|
Q

I

V

L

L

H

F

T

S

T

E

A

D

S

D

A

V

G

G

T

K

P

N

K
|
K

V

T

S

E

S

V

A

I

A

K

E

R

R

E

I

L

H

L

A

K

L

R

N

N

P

S

A

E

T

I

R

S

L

V

A

S

L

E

H

I

P

A

F

L

H
x
N

L
x
I

D

N

E

D

K

Y

N

T

A

D

E

L

A

H

L

K

I

V

A

P

R

E

Y

A

D

D

-

I

F

W

V

V

I

V

D

S

A
|
A

T
x
D

D
x
H

S

P

F

F

R

N

A

L

K

I

F

N

L

W

I

V

A

N

K

K

T

Y

C

C

H

V

R

R

E

A

E

N

K

Q

P

P

Y

Y

S

I

H

N

A

A

G

G

I

-

T

-

S

-

Y

-

Y

Y

G

V

H

N

T

D

I

I

T

A

V

V

-

F

-

G

-

P

-

L

-

Y

Q

V

P

P

G

G

K

K

T

T

A

G

C
|
C

Y

Y

N

E

C
|
C

I

Q

F

K

H

K

E

E

T

N

E

I

P

D

A

H

A

K

E

I

A

K

D

L

A

I

H

N

L

S

T

R

V

F

P

K

A

P

G

A

P

T

L

F

G

A

P

P

L

V

P

N

G

N

I

V

I

A

G

A

S

A

I

L

Q

C

A

A

E

D

A

V

L

I

K

K

H

F

I

I

L

G

S

K

I

Y

G

S

K

E

G

P

L

L

H

S

-

L

N

N

T

K

L

R

L

I

S

G

L

I

D

W

L

S

L

D

T

E

M

I

T

K

F

I

R

H

S

S

I

Q

P

N

V

M

N

G

P

R

D

S

P

P

N

V

C
|
C

P

S

I

V

C
|
C

G

G

active site: R157 (= R72)
binding adenosine-5'-triphosphate: G124 (= G39), D146 (= D61), N154 (= N69), R157 (= R72), Q158 (= Q73), K170 (= K85), N193 (≠ H108), I194 (≠ L109), A213 (= A127), D214 (≠ T128), H215 (≠ D129)
binding zinc ion: C257 (= C170), C260 (= C173), C334 (= C246), C337 (= C249)

Query Sequence

>WP_012465627.1 NCBI__GCF_000020465.1:WP_012465627.1
MALNDEQRKRFTRHLSMDEIGEKGQEKLLQAKVLIVGAGGLGSPAAFYLAAAGIGTLGLA
DGDRVDLSNLQRQILHTTASAGTPKVSSAAERIHALNPATRLALHPFHLDEKNAEALIAR
YDFVIDATDSFRAKFLIAKTCHREEKPYSHAGITSYYGHTITVQPGKTACYNCIFHETEP
AAEADAHLTVPAGPLGPLPGIIGSIQAAEALKHILSIGKGLHNTLLSLDLLTMTFRSIPV
NPDPNCPICGKKN

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory